深圳市成人B期心力衰竭患病情况流行病学调查

Prevalence and epidemiological investigation of Stage B heart failure in Shenzhen adults

目的了解深圳市成人B期心力衰竭的流行病学特征及相关影响因素,为心力衰竭防控政策的制定提供参考依据。方法数据来源于2021年深圳市心力衰竭流行病学调查,采用多阶段分层随机抽样的方法,对6128名≥18岁深圳市常住居民进行一般信息问卷调查、身体测量和超声心动图检查,获取心脏结构及功能相关信息。使用R 4.1.3软件进行基于复杂抽样设计的Rao-Scott χ^(2)检验、多因素二分类logistic回归和无序多分类logistic回归,并进行敏感性分析。结果加权后,深圳市成人B期心力衰竭患病率为14.45%(95%CI:12.88%~16.12%),心脏结构和功能均异常、仅结构异常和仅功能异常的患病率分别为1.33%(95%CI:0.92%~1.84%)、9.77%(95%CI:8.44%~11.23%)和3.35%(95%CI:2.80%~3.96%)。多因素分析结果显示,45~64岁(OR=1.51)、65岁及以上(OR=2.85)、离退休或无业或失业(OR=1.63)、超重(OR=2.11)、肥胖(OR=4.09)、高血压(OR=1.65)和其他心血管疾病(OR=4.27)与B期心力衰竭高风险相关,血脂异常(OR=0.77)与B期心力衰竭低风险相关,均有统计学意义(P<0.05)。结论深圳市B期心力衰竭普遍流行,应积极采取措施预防或延缓其进展为有症状性心力衰竭。

Objective To understand the prevalence or epidermiological characteristics and relative factors of stage B heart failure in the adults of Shenzhen and provide the reference basis for developing the heart failure prevention and control policies.Methods The data were from the 2021 Shenzhen Heart Failure Epidemiologic Survey,and the multistage stratified random sampling method was used to select 6128 reidents(≥18 years old)as the subjects.The investigation was performed with the general information questionnaire,physical measurements,and echocardiography examinations to obtain information about heart structure and function.Rao-Scott χ^(2) test,multifactorial binary logistic regression,and unordered multinomial logistic regression based on a complex sampling design were used to analyze the sensitivity.The used software was R 4.1.3.Results After weighted,the prevalence of stage B heart failure in Shenzhen was 14.45%(95%CI:12.88%-16.12%),and the prevalence rates of both heart structural and functional abnormalities,structural abnormalities and functional abnormalities were 1.33%(95%CI:0.92%-1.84%),9.77%(95%CI:8.44%-11.23%)and 3.35%(95%CI:2.80%-3.96%),respectively.Multivariate analysis showed that aged 45 to 64 years(OR=1.51),65 years and older(OR=2.85),retired or jobless or unemployed(OR=1.63),overweight(OR=2.11),obesity(OR=4.09),hypertension(OR=1.65)and other cardiovascular diseases(OR=4.27)were associated with higher risk of stage B heart failure,and dyslipidemia(OR=0.77)was associated with lower risk of stage B heart failure(P<0.05).Conclusion Stage B heart failure is generally prevalent in Shenzhen,and active measures should be taken to prevent or delay its progression to symptomatic heart failure.