1972-2021年江苏省启东市膀胱癌发病流行趋势分析

Incidence Trend of Bladder Cancer in Qidong City,Jiangsu Province from 1972 to 2021

[目的]分析启东市1972-2021年全人群膀胱癌的发病特征及趋势。[方法]使用来自启东市肿瘤登记数据库1972-2021年膀胱癌的发病资料,计算膀胱癌的粗发病率、中国人口标化率(中标率)、世界人口标化率(世标率)等统计指标。采用Joinpoint 4.9.1.0软件进行趋势分析,计算膀胱癌发病率的年度变化百分比(APC)。[结果]启东市1972-2021年膀胱癌共发病2981例,占全部恶性肿瘤发病的2.02%;50年间膀胱癌粗发病率为5.31/10万,中标率为1.83/10万,世标率为3.11/10万,35~64岁截缩发病率为3.91/10万,0~74岁累积发病率为0.35%,膀胱癌累积发病风险为0.35%。男性发病率明显高于女性,粗发病率、中标率和世标率的性别比依次为3.68∶1、4.37∶1和4.40∶1。随着年龄的增长,膀胱癌发病率不断增加,膀胱癌发病年龄也略有提升。膀胱癌总体、男女性以及各个年龄组的发病率在50年间均有明显的上升趋势。[结论]50年间启东市全人群膀胱癌的发病率明显上升,男性发病率高于女性,高年龄组发病率高于低年龄组,应当继续重视尤其是针对重点人群膀胱癌的防治研究。

[Purpose]To analyze the incidence trend of bladder cancer in the whole population of Qidong from 1972 to 2021.[Methods]The incidence data of bladder cancer from 1972 to 2021 from the Qidong Cancer Registry database were used to calculate statistical indicators such as crude rate(CR),age-standardized rate by Chinese standard population(ASRC),age-standardized rate by world standard population(ASRW),and so on.Trend analysis was performed using Joinpoint 4.9.1.0 software to calculate the annual percentage change(APC)of bladder cancer incidence rates.[Results]In Qidong City,there were 2981 cases of bladder cancer from 1972 to 2021,accounting for 2.02%of all malignant tumors;the total CR of bladder cancer was 5.31/105,ASRC was 1.83/105,ASRW was 3.11/105,the truncated incidence of bladder cancer in the age group of 35~64 years old was 3.91/105,the cumulative incidence of bladder cancer in the age group of 0~74 years old was 0.35%,and the cumulative risk of bladder cancer was 0.35%.Incidence rates were significantly higher in male than female,with sex ratios of 3.68,4.37 and 4.40 for CR,ASRC and ASRW.The incidence rates of bladder cancer in all age groups continued to increase with increasing age.There was a slight increase in the age of onset of bladder cancer.The incidence of bladder cancer overall,in both sexes and in all age groups had a significant upward trend over the 50-year period.[Conclusion]The incidence of bladder cancer in the whole population of Qidong City has increased considerably during the past 50 years,with the incidence rate of males higher than that of females,the higher age group higher than that of the lower age group.Continued attention should be paid to the research of bladder cancer prevention and treatment especially for the high risk populations.