血清β_(2)-微球蛋白联合免疫球蛋白检测在多发性骨髓瘤早期诊断中的应用效果

Application of Serumβ_(2)-microglobulin Combined with Immunoglobulin Detection in the Early Diagnosis of Multiple Myeloma

目的:探讨血清β_(2)-微球蛋白联合免疫球蛋白检测在多发性骨髓瘤早期诊断中的应用效果.方法:选取2020年1月-2022年10月来院就诊的100例患者为研究对象,观察组(n=50)为多发性骨髓瘤来院接受治疗的患者;对照组(n=50)为来院接受健康体检的健康人员.2组患者均接受血清β2-微球蛋白联合免疫球蛋白检测,针对检测结果展开对照分析.结果:观察组血清β_(2)-微球蛋白、免疫球蛋白A、免疫球蛋白G、乳酸脱氢酶、超敏C-反应蛋白测定结果均高于对照组,组间差异有统计学意义(P<0.05);与观察I组相比,其他2组测定结果均更高,组间差异有统计学意义(P<0.05);与观察Ⅱ组相比,观察Ⅲ组各项测定结果均更高,组间差异有统计学意义(P<0.05);与治疗无效组相比,治疗有效组各项指标测定该结果均更低,组间差异有统计学意义(P<0.05).结论:应用血清β_(2)-微球蛋白联合免疫球蛋白检测方法有助于提升多发性骨髓瘤早期诊断效果,同时也有助于评估患者的治疗效果,值得临床推广.

Objective:To investigate the effect of serumβ_(2)-microglobulin combined with immunoglobulin detection in the early diagnosis of multiple myeloma.Methods:A total of 100 patients who came to the hospital from January 2020 to October 2022 were selected as the study objects,and the observation group(n=50)was patients who came to the hospital for treatment of multiple myeloma.The control group(n=50)was the healthy people who came to the hospital for physical examination.Serumβ_(2)-microglobulin combined with immunoglobulin was detected in both groups,and control analysis was performed on the detection results.Results:The results of serumβ_(2)-microglobulin,immunoglobulin A,immunoglobulin G,lactate dehydrogenase and hypersensitive C-reactive protein in observation group were higher than those in control group,and the differences were statistically significant(P<0.05).Compared with observation group I,the results of the other two groups were higher,and the differences between groups were statistically significant(P<0.05).Compared with observation group I,the results of observation group II were higher,and the differences between groups were statistically significant(P<0.05).Compared with the ineffective treatment group,the results of all indexes measured in the effective treatment group were lower,and the differences between the groups were statistically significant(P<0.05).Conclusion:The clinical effect of acupuncture combined with modern rehabilitation therapy for patients with limb dysfunction after stroke is significant,which can effectively reduce the patient's degree of neurological deficit,improve their ability of daily living,and promote the recovery of their limb motor function and overall bodyfunction.