中国男男性行为者rush poppers使用情况的Meta分析

Meta-analysis of rush poppers usage among men who have sex with men in China

目的 系统评价我国MSM亚硝酸盐吸入剂(rush poppers,Rush)的使用情况,为制定有针对性的干预措施提供科学依据。方法 计算机检索CBM、CNKI、VIP、万方、Embase、PubMed、Cochrane Library、和Web of Science数据库中关于我国MSM Rush使用情况的相关文献,检索时间为建库至2024年2月,使用stata16.0软件进行Meta分析。结果 最终纳入39篇文献,共包含42 620例MSM。结果显示,中国MSM Rush的使用率为29.0%(95%CI:25.0%~33.0%)。亚组分析结果显示,调查时间在2016年前为29.2%(95%CI:25.0%~33.4%),2016年以后为31.6%(95%CI:24.3%~39.0%);来自北方为34.7%(95%CI:30.3%~39.2%),南方为26.1%(95%CI:21.2%~31.1%);婚姻状态未婚为29.8%(95%CI:25.4%~34.3%),已婚、离异或丧偶为19.5%(95%CI:15.9%~23.1%);年龄≤25岁为29.7%(95%CI:22.0%~37.4%),>25岁为26.2%(95%CI:19.7%~32.8%);月收入<3 000元为25.2%(95%CI:17.4%~32.9%),≥3 000元为34.7%(95%CI:28.1%~41.3%);文化程度高中及以下为23.4%(95%CI:18.9%~27.8%),大专及以上为28.6%(95%CI:23.8%~29.5%)。结论 中国MSM Rush的使用率较高,其中2016年以后、北方、未婚、年龄≤25岁、月收入≥3 000,文化程度在大专及以上的使用率较高,应该密切关注以上重点人群,采取干预措施,减少Rush在MSM中的使用。

Objective To systematically evaluate the usage of nitrite inhalants(rush poppers)among men who have sex with men(MSM)in China,and to provide a scientific basis for targeted interventions.Methods Relevant literature on the usage of rush poppers among MSM in China was retrieved from databases including China Biology Medicine disc(CBM),China National Knowledge Internet(CNKI),VIP Chinese Journal Service Platform,Wanfang Data Knowledge Service Platform,Embase(via OVID),PubMed,Cochrane Library,and Web of Science.The search period ranged from the inception to February 2024.Meta-analysis was conducted using Stata 16.0 software.Results A total of 39 articles with 42620 MSM participants were included in the analysis.The results showed that the prevalence of rush poppers usage among Chinese MSM was 29.0%(95%CI:25.0%-33.0%).Subgroup analysis revealed that the rate was 29.2%(95%CI:25.0%-33.4%)for investigations conducted before 2016,and 31.6%(95%CI:24.3%-39.0%)for investigations conducted after 2016.The usage rate was 34.7%(95%CI:30.3%-39.2%)for participants from northern China,and 26.1%(95%CI:21.2%-31.1%)for those from southern China.Unmarried participants had a rate of 29.8%(95%CI:25.4%-34.3%),while married,divorced,or widowed participants had a rate of 19.5%(95%CI:15.9%-23.1%).Among participants aged≤25 years,the rate was 29.7%(95%CI:22.0%-37.4%),while among those>25 years,it was 26.2%(95%CI:19.7%-32.8%).Participants with a monthly income<3000 RMB had a usage rate of 25.2%(95%CI:17.4%-32.9%),while those with an income≥3000 RMB had a rate of 34.7%(95%CI:28.1%-41.3%).Participants with a high school education or below had a rate of 23.4%(95%CI:18.9%-27.8%),while those with a college education or above had a rate of 28.6%(95%CI:23.8%-29.5%).Conclusions The usage rate of rush poppers among Chinese MSM is relatively high.It is important to pay close attention to key populations,such as those from northern China,unmarried individuals,those aged≤25 years,those with a monthly income≥3000 RMB,and those with a college education or above.Intervention measures should be implemented to reduce the usage of rush poppers among MSM.