摘要
Monitoring the electrophysiology activity of neurons and blood calcium signals can enable a better understanding of disease-related neural system circuits.However,currently,in situ calcium ion monitoring tools are scarce and exhibit low integration and limited sensitivity.In this letter,we propose an implantable probe with an integrated in situ Ag/AgCl reference electrode(ISA/ARE)that can monitor action potential(AP)and Ca^(2+) concentrations.
基金
supported by the STI 2030-Major Projects (Nos. 2022ZD0208601 and 2022ZD0208600)
the National Key R&D Program of China (Nos. 2022YFF120301 and2020YFB1313502)
the Fundamental Research Funds for the Central Universities
the Strategic Priority Research Program of Chinese Academy of Sciences (Nos. XDA25040100, XDA25040200, and XDA25040300)
the National Natural Science Foundation of China(No. 42127807-03)
the Shanghai Municipal Science and Technology Major Project (No. 2021SHZDZX)
China Postdoctoral Science Foundation (No. 2023M732197)
the Center for Advanced Electronic Materials and Devices (AEMD) of Shanghai Jiao Tong University,China
