舒更葡糖钠应用于老年患者深肌松腹腔镜手术的效果分析

Analysis of the Effect of Sugammadex Sodium Application in Deep Muscle Relaxation Laparoscopic Surgery in Elderly Patients

目的 分析舒更葡糖钠应用于老年患者深肌松腹腔镜手术的效果。方法 方便选择徐州市肿瘤医院于2023年1—10月收治的82例行腹腔镜手术的老年患者为研究对象,以随机数表法划分为两组,各41例。观察组行舒更葡糖钠拮抗肌松,对照组行新斯的明+阿托品拮抗肌松。对比两组肌松恢复指标、肌松残余情况及并发症。结果 观察组拔管时间、麻醉恢复室停留时间、肌肉恢复指数和TOF恢复至0.9的时间均优于对照组,差异有统计学意义(t=9.383、10.830、11.110、13.181,P均<0.05)。用肌松拮抗药5、15 min时,观察组肌松残余率分别为12.20%、0,低于对照组的41.46%、26.83%,差异有统计学意义(χ^(2)=8.945、12.704,P均<0.05)。观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论 予以老年患者深肌松腹腔镜手术舒更葡糖钠拮抗肌松,可缩短患者拔管和麻醉恢复室停留时间,肌松残余率较低,并发症较少。

Objective To analyze the effect of sugammadex sodium applied to deep muscle relaxation laparoscopic surgery in elderly patients.Methods Eighty-two elderly patients admitted to Xuzhou Cancer Hospital for laparoscopic surgery from January to October 2023 were conveniently selected as the study subjects,and were divided into two groups of 41 cases each by random number table method.In the observation group,sugammadex sodium was used to antagonize muscle relaxation,and in the control group,neostigmine + atropine was used to antagonize muscle relaxation.The two groups were compared in terms of muscle relaxation recovery indexes,muscle relaxation residual condition and complications.Results The observation group's extubation time,anesthesia recovery room stay time,muscle recovery index and TOF recovery to 0.9 were better than that of the control group,the differences were statistically significant(t=9.383,10.830,11.110,13.181,all P<0.05).At 5 and 15 min with muscarinic antagonist,the residual rate of muscle relaxation in the observation group was 12.20% and 0,respectively,which were lower than that in the control group,which were 41.46% and 26.83%,the differences were statistically significant(χ^(2)=8.945,12.704,both P<0.05).The total complication rate of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Antagonizing muscle relaxation with deep muscle relaxation laparoscopic surgery with sugammadex sodium in elderly patients can shorten the time of patients' extubation and anesthesia recovery room stay,with lower residual rate of muscle relaxation and fewer complications.