钬激光前列腺剜除术治疗良性前列腺增生效果观察

Effect of Holmium Laser Enucleation of Prostate on Benign Prostatic Hyperplasia

目的探究钬激光前列腺剜除术(HoLEP)治疗良性前列腺增生(BPH)的效果及对术后恢复、生活质量和性功能的影响。方法选择2021年1月至2024年2月收治的BPH患者340例,按照治疗方式不同分为研究组172例和对照组168例。研究组给予HoLEP治疗,对照组给予等离子前列腺剜除术(PKEP)。比较2组BPH患者临床疗效、术后恢复情况[术后血红蛋白下降量、住院时间、膀胱冲洗时间、导尿管留置时间、最大尿流率(Q_(max))、国际前列腺症状评分(IPSS)和膀胱残余尿量]、生活质量[健康调查简表(SF-36)]和性功能情况。结果研究组总有效率[99.42%(171/172)]高于对照组[95.83(161/168)](P<0.05)。研究组术后血红蛋白下降量和膀胱残余尿量均少于对照组,住院时间、术后膀胱冲洗时间和导尿管留置时间均短于对照组,IPSS低于对照组,Q_(max)高于对照组(P<0.01)。术后,研究组生理功能、躯体疼痛和精力等SF-36量表评分高于对照组(P<0.01)。2组术后4个月并发症发生率比较差异无统计学意义(P>0.05)。2组术后4个月性功能组内与组间比较差异无统计学意义(P>0.05)。结论HoLEP治疗BPH临床效果好,可改善术后血红蛋白等指标,提升生活质量,且并发症发生风险小,不影响性功能。

Objective To investigate the effect of Holmium laser enucleation of the prostate(HoLEP)on benign pros-tatic hyperplasia(BPH)and its effect on postoperative recovery,quality of life and sexual function.Methods A total of 340 patients with BPH treated from January 2021 to February 2024 were selected and divided into research group(n=172)and control group(n=168)according to different treatment methods.The research group was treated with HoLEP and the control group was treated with plasma kinetic enucleation of the prostate(PKEP).The clinical efficacy,postoperative recovery[postop-erative hemoglobin decline,length of hospital stay,bladder irrigation time,catheter retention time,maximum urinary flow rate(Q_(max)),International Prostatic symptom score(IPSS)and bladder residual urine volume],quality of life[The MOS 36-Item Short-Form Health Survey(SF-36)]and sexual function were compared between the two groups.Results The total effective rate of the research group[99.42%(171/172)]was higher than that of the control group[95.83(161/168)](P<0.05).The postoperative hemoglobin decline and bladder residual urine volume in the research group were lower than those in the control group,the length of hospital stay,postoperative bladder irrigation time and catheter retention time were shorter than those in the control group,the IPSS was lower than that in the control group,and the Q_(max)was higher than that in the control group(P<0.01).After surgery,the SF-36 scores of physiological function,physical pain and energy in the research group were higher than those in the control group(P<0.01).There was no significant difference in the complications between the two groups at 4 months af-ter surgery(P>0.05).There was no significant intragroup and intergroup difference in sexual function at 4 months after sur-gery(P>0.05).Conclusion HoLEP has good clinical effect in the treatment of BPH,which can improve postoperative he-moglobin and other indexes,improve quality of life,and reduce the risk of complications without affecting sexual function.