运动锻炼与康复治疗对中风病人影响的Meta分析

Meta Analysis of Effect of Exercise training and Rehabilitation Therapy on Stroke Patients

研究旨在评估运动锻炼和康复治疗对中风患者最大有氧代谢能力和运动机能的影响.对PubMed、EBSCO Host、Elsevier、Springer等数据库进行了全面检索,收集了截至2023年的关于运动干预中风患者的随机对照实验文献,并对这些文献进行Cochrane偏倚风险评估工具的方法学质量评价后,使用Rev Man软件对数据进行了统计学处理分析. Meta分析共纳入文献10篇,总样本量368人,均为中风病人.通过分析发现文献对中风患者最大有氧代谢能力具有异质性,而对中风患者运动机能的异质性可以忽略,采用随机效应模型进行分析,加强运动锻炼组与日常康复治疗组比较,最大有氧代谢能力MD=2.36(95%CI,I^(2)=69%,P=0.000 7),6 min走路距离MD=51.36(95%CI,I^(2)=33%,P=0.000 2).综合这些发现得出:加强运动锻炼对于提高中风患者的最大有氧代谢能力和运动机能具有显著的正面影响,为中风患者的康复治疗提供了有力的支持和指导.

The aim of this study was to assess the effects of exercise training and rehabilitation therapy on maximal aerobic capacity and motor function in stroke patients.To this end,through a comprehensive search of PubMed,EBSCO Host,Elsevier,Springer and other databases,the literature of randomized controlled trials on exercise intervention in stroke patients up to 2023 was collected.After evaluating the methodological quality of the Cochrane bias risk assessment tool,statistical analysis of the data was performed using RevMan software.A total of 10 literatures were included in the meta-analysis,with a total sample size of 368 patients,all of whom were stroke patients.Through the analysis,it was found that the literature had heterogeneity in the maximum aerobic capacity of stroke patients,while the heterogeneity in motor function of stroke patients could be ignored.The random effects model was used for analysis,and the comparison between the intensive exercise group and the daily rehabilitation treatment group showed that the maximum aerobic capacity MD=2.36(95%CI,I2=69%,P=0.0007).6 min walking distance MD=51.36(95%CI,I2=33%,P=0.0002).Taking these findings into account,it is concluded that strengthening exercise has a significant positive impact on improving the maximum aerobic capacity and motor function of stroke patients,which provides a strong support and guidance for rehabilitation treatment of stroke patients.