巨细胞血管母细胞瘤的临床资料及影像学检查特征

Clinical data and imaging examination features of giant cell hemangioblastoma

目的探讨巨细胞血管母细胞瘤(GCAB)的临床资料及影像学检查表现。方法回顾性选取2017年5月至2021年7月广州中医药大学附属佛山中医院经手术病理检查证实的3例GCAB患者的临床资料及影像学检查表现。结果3例GCAB患者均为年轻男性,均发生在左膝关节,其中2例在软组织,1例在骨。2例病灶边界清楚,1例与邻近水肿区分界模糊。2例病灶密度或信号不均,其中1例CT平扫骨质破坏区内见斑点状稍高密度影,1例T2加权脂肪抑制成像呈高低混杂信号;1例信号均匀。增强CT扫描1例呈轻度欠均匀强化,1例明显均匀强化,1例未进行增强CT扫描。结论GCAB可发生在骨或软组织,临床资料及影像学检查表现特征性不明显,最终诊断需要依靠病理学检查证实。

Objective To investigate the clinical data and imaging examination findings of giant cell hemangioblastoma(GCAB).Methods The clinical data and imaging examination findings of 3 patients with GCAB confirmed by surgery and pathology in Foshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine were retrospectively analyzed from May 2017 to July 2021.Results All 3 GCAB patients were young men and all occurred in the left knee joint,2 in soft tissue and one in bone.The boundary of the lesions was clear in 2 cases,and the boundary between the lesions and the adjacent edema area was blurred in 1 case.The density or signal intensity of the lesions was heterogeneous in 2 cases,of which 1 case showed slightly high density in the bone destruction area on plain CT scan,and 1 case showed mixed high and low signal on T2-weighted fat suppression imaging.The signal intensity was homogeneous in 1 case.Enhanced CT scan showed mild uneven enhancement in 1 case,obvious homogeneous enhancement in 1 case,and no enhanced CT scan in 1 case.Conclusion GCAB can occur in bone or soft tissue.The clinical data and imaging findings are not specific,and the final diagnosis depends on pathological examination.