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冠心宁片治疗老年冠心病患者的疗效

Effects of Guanxinning Tablets on elderly patients with coronary heart disease
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摘要 目的观察冠心宁片治疗老年冠心病患者的疗效。方法选取2022年1月至6月来浙江省立同德医院就诊的200例老年冠心病患者按治疗方法分为试验组和对照组,2组均予常规西药治疗,试验组加用冠心宁片,每次4片,每日3次口服,治疗时间12周。结果治疗前2组患者心绞痛积分、中医证候积分及内在能力评估各维度差异无统计学意义(P均>0.05)。治疗12周后,2组的心绞痛积分、中医证候积分和内在能力的认知、运动、心理维度均较治疗前改善(P均<0.05)。试验组的心绞痛积分(t=7.366)、中医证候积分(t=8.038)和内在能力的运动(t=2.481)、心理(t=5.066)维度改善情况均优于对照组(P均<0.05)。结论冠心宁片能够改善老年冠心病患者的心绞痛症状和中医证候,维护内在能力,有助于整体健康。 Objective To observe the curative effect and intrinsic capacity change in elderly patients with coronary heart disease treated with Guanxinning Tablets.Methods A total of 200 elderly patients with coronary heart disease were randomly divided into an experimental group and a control group.Both groups were given con-ventional western medicine treatment,and the experimental group was added with Guanxinning Tablets,four tablets each time,three times a day by oral administration.The course of treatment was 12 weeks.Results There were no significant differences in angina score,traditional Chinese medicine(TCM)syndrome score and intrinsic capacity between the two groups before treatment(all P>0.05).After 12 weeks of treatment,the angina score,TCM syndrome score and the cognitive,motor and psychological dimensions of intrinsic capacity were all improved in the two groups(all P<0.05).The improvement of angina score(t=7.366),TCM syndrome score(t=8.038),exercise(t=2.481)and psychological(t=5.066)dimensions of intrinsic capacity in the experimental group were better than those in the control group(all P<0.05).Conclusion Guanxinning Tablets can improve angina pectoris symptoms and TCM symptoms of elderly patients with coronary heart disease,maintain intrinsic capacity and contribute to overall health.Under the background of healthy aging,the method of quantitative evaluation of intrinsic capacity provides a new idea for the evaluation of curative effect of traditional Chinese medicine.
作者 王结胜 金东 彭鹏 刘伟 王钦贤 Wang Jiesheng;Jin Dong;Peng Peng;Liu Wei;Wang Qinxian(Department of Cadres,Tongde Hospital of Zhejiang Province,Hangzhou,Zhejiang 310012,China)
出处 《中国药物与临床》 CAS 2024年第13期853-856,共4页 Chinese Remedies & Clinics
基金 浙江省医药卫生科技项目(2024KY883) 浙江省医学会临床科研项目(2021ZYC-A61)。
关键词 冠心宁片 老年 冠心病 治疗结果 内在能力 Guanxinning tablets Elderly Coronary disease Treatment outcome intrinsic capacity
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