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胰腺癌术后患者的预后分析

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摘要 目的分析胰腺癌术后患者的预后及影响因素。方法纳入2017年10月至2021年6月在首都医科大学附属北京朝阳医院完成胰腺癌根治切除术的患者147例为研究对象,收集病历资料并进行随访。采用Kaplan-Meier生存曲线计算无病生存期(DFS)和总生存期(OS);采用Log-rank单因素分析,采用COX回归模型进行多因素分析。结果患者中位年龄为66(31~92)岁,中位DFS和OS分别为11.1个月和18.7个月。仅有33例患者(22.4%)接受了辅助化疗,进行辅助化疗患者的生存期(32.4个月)显著优于未进行辅助化疗的患者(16.7个月),差异有统计学意义(P=0.028)。不同病理类型,预后显著不同(P<0.001)。结论胰腺癌术后患者的总体预后不乐观,术后辅助化疗可改善预后,但实际临床上胰腺癌术后辅助化疗率很低,有待提高。胰腺癌术后患者病理类型不同,预后显著不同。
出处 《中国临床医生杂志》 2024年第8期927-930,共4页 Chinese Journal For Clinicians
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