6674例住院患者含冰片中成药应用现状和合理性分析

Application Status and Rationality Analysis of Chinese Patent Medicines Containing Borneol in 6674 Inpatients

目的:分析含冰片中成药的临床应用现状及合理性,为规范临床合理用药提供参考。方法:检索2022年1月~2023年5月某医院信息系统中含冰片中成药的住院患者病历信息,统计患者基本情况、临床诊断、遴选药品、重复用药/联合用药、用药疗程等信息,采用描述性分析对医嘱进行回顾性分析及合理性评价。结果:在住院药房中的11种含冰片中成药均为口服剂型;6674例住院患者使用了含冰片中成药8050例次,其中以复方丹参滴丸最为常见,共1513例次(18.80%)。不合理用药方面,用药疗程不适宜793例次(11.88%),重复用药/联合用药不适宜199例次(2.98%),临床诊断书写不全70例次(1.05%),遴选药品不适宜8例次(0.12%)。未发现患者出现药品不良反应。结论:含冰片中成药的临床应用在用药疗程、剂量和重复用药/联合用药等方面存在一定程度的不合理现象,需要强化监督和管理以确保用药的安全性和有效性。

Objective:To analyze the current status and rationality of clinical use of Chinese patent medicines containing borneol,so as to provide reference for standardizing its clinical application.Methods:The medical records of inpatients with borneol prescription from January 2022 to May 2023 in a hospital information system were retrieved to summarize basic information,clinical diagnosis,drug selection,repeat/combination medications,course of treatment,etc.Descriptive statistics were used to perform retrospective analysis and evaluate the rationality of medical orders.Results:There were 11 Chinese patent medicines containing borneol prescribed in inpatient dispensary and all of them were oral dosage form.Chinese patent medicines containing borneol were used by 6674 patients for 8050 cases,with compound Danshen dripping pills as the most frequently used medication which was used for 1513 cases(18.80%).In the aspect of irrational drug use,inappropriate course of treatment was identified in 793 cases(11.88%),inappropriate repeat/combination medications in 199 cases(2.98%),incomplete records of clinical diagnosis in 70 cases(1.05%),and inappropriate drug selection in 8 cases(0.12%).No adverse drug reactions were observed in the patients.Conclusion:The clinical use of Chinese patent medicines containing borneol is partly irrational in terms of course of treatment,dosage and repeat/combination medications,and therefore relevant supervision and management need strengthening to ensure the safety and efficacy of drug use.