国家集采对骨科Ⅰ类切口手术预防使用抗菌药物的影响

The Influence of National Centralized Procurement on the Prevention and Use of Antibiotics in Orthopedic Class Ⅰ Incision Surgery

目的探讨国家集采对骨科Ⅰ类切口手术预防使用抗菌药物的影响。方法以2021年10月第5批抗菌药物国家集采为政策执行点,分别选取集采前(2021年1—6月)骨科Ⅰ类切口手术预防使用抗菌药物患者17例和集采后(2022年1—6月)骨科Ⅰ类切口手术预防使用抗菌药物患者17例,对抗菌药物的选择、术前用药时机、用药疗程、药品费用等数据进行回顾性分析。结果国家集采后,骨科Ⅰ类切口手术预防使用抗菌药物集采品种注射用头孢唑林钠占64.72%,给药时间主要在术前30 min至1 h,用药疗程≤24 h患者比例提高至70.59%,抗菌药物使用费用降低80.12%。结论国家集采后,骨科Ⅰ类切口手术抗菌药物的选择更合理,切实减轻了患者的用药负担,有效节省了医保资金。

Objective To explore the effect of national collection on prophylactic use of antibiotics in orthopedic surgery with type Ⅰ incision.Methods Taking October 2021 as the fifth batch of national collection of antimicrobials as the policy implementation point,17 patients with orthopaedic type Ⅰ incision surgical prophylaxis using antimicrobials before collection(January to June 2021)and 17 patients with orthopaedic type Ⅰ incision surgical prophylaxis using antimicrobials after collection(January to June 2022)were selected.The data of selection of antibiotics,timing of preoperative administration,duration of administration and cost of drugs were analyzed retrospectively.Results After the national centralized purchase,the prophylactic use of antibacterial drugs in orthopedic Class Ⅰ incision surgery accounted for 64.72%,the administration time was mainly 30min to 1 h before the operation,the proportion of medication duration≤24 h increased to 70.59%,and the use cost of antibacterial drugs decreased by 80.12%.Conclusion After the national centralized purchase,the selection of antibacterial drugs is more reasonable,which effectively reduces the drug burden of patients and effectively saves medical insurance funds.