基层医院终末期肾病患者不同透析方式的临床疗效研究

Clinical Efficacy Studies of Different Dialysis Modalities in Patients with End-Stage Renal Disease in Primary Hospitals

目的 探讨基层医院终末期肾病(End-stage Renal Disease,ESRD)患者应用不同透析方式的治疗效果。方法 目的选取织金县人民医院于2023年1—12月收治的137例ESRD患者为研究对象,按不同透析方式分成A组(n=39)、B组(n=45)、C组(n=53)。A组每周透析两次,4.5 h/次;B组每周透析两次,4 h/次;C组每周透析3次,4 h/次。对比3组营养指标、炎症指标及并发症发生情况。结果 治疗后,3组营养指标水平较治疗前提高,A组营养指标水平高于B组,差异有统计学意义(P均<0.05),而A组与C组比较,差异无统计学意义(P>0.05)。治疗后,3组炎症指标水平均低于治疗前,A组项炎症指标水平优于B组,差异有统计学意义(P均<0.05),而A组与C组比较,差异无统计学意义(P>0.05)。A组并发症总发生率(10.26%)低于B组(28.89%)、C组(30.19%),差异有统计学意义(χ^(2)=5.241,P<0.05)。结论 对于基层医院ESRD患者,选择每周透析两次,4.5 h/次的透析方式,总体效果优于每周2次、4 h/次的透析患者,而与每周3次,4 h/次的透析患者的治疗效果相当,但每周透析两次,4.5 h/次的透析方式可降低透析并发症的发生率。

Objective To investigate the therapeutic effect of different dialysis methods in patients with End-stage renal disease (ESRD) in primary hospital.Methods A total of 137 ESRD patients admitted to Zijin County People's Hospital from January to December 2023 were purposely selected as study objects and divided into Group A (n=39),Group B (n=45),and Group C (n=53) according to different dialysis methods.Group A was dialyzed twice a week,4.5h/times;Group B was dialyzed twice a week,4 h/times;Group C was dialyzed three times a week,4 h/times.Nutritional indexes,inflammatory indexes and complications occurred in the 3 groups were compared.Results After treatment,the level of nutritional indicators in the 3 groups was higher than that before treatment,and the level of nutritional indicators in group A was higher than that in group B,and the difference was statistically significant (all P<0.05),while 3 was no statistically significant difference when comparing group A with group C (P>0.05).After treatment,the level of inflammatory indexes in the three groups was lower than that before treatment,and the level of inflammatory indexes in group A was better than that in group B,and the differences were statistically significant (all P<0.05),while there was no statistically significant difference when comparing group A with group C (P>0.05).The total incidence of complications in group A (10.26%) were lower than that in group B (28.89%) and group C (30.19%),and the differences were statistically significant (χ^(2)=5.241,P<0.05).Conclusion For ESRD patients in primary hospitals,choosing dialysis twice a week at 4.5 h/times has better overall results than dialysis patients on dialysis twice a week at 4 h/times,but comparable treatment outcomes to those on dialysis three times a week at 4 h/times,but dialysis twice a week at 4.5 h/times can reduce the incidence of dialysis complications.