卡前列素氨丁三醇联合宫腔球囊填塞治疗前置胎盘剖宫产产后出血对出血量情况的影响分析

Effect of Carboprost Tromethamine Injection Combined with Balloon Tamponade on Hemorrhage after Caesarean Section of Placenta Previa

目的 探究与分析卡前列素氨丁三醇联合宫腔球囊填塞治疗前置胎盘剖宫产产后出血对出血量情况的影响。方法 目的选取2020年3月—2022年8月山东省潍坊市临朐县人民医院收治的80例前置胎盘剖宫产产后出血患者为研究对象并按照治疗方法不同分为两组,每组40例,对照组采取缩宫素联合卡前列素氨丁三醇治疗,观察组加用宫腔球囊填塞治疗,对比两组临床疗效、手术时间、首次月经时间、白细胞计数、血清C反应蛋白、出血量、住院时间及输血率、子宫切除率。结果 观察组临床总有效率为95.00%,较对照组(77.50%)高,差异有统计学意义(χ^(2)=5.165,P<0.05)。观察组手术时间、首次月经时间、白细胞计数、血清C反应蛋白水平、术中出血量、产后2 h出血量、产后24 h出血量、住院时间均优于对照组,差异有统计学意义(P均<0.05)。结论 卡前列素氨丁三醇联合宫腔球囊填塞治疗前置胎盘剖宫产产后出血可获得更好的临床疗效,围术期指标表现较好,同时可降低输血率以及子宫切除率,可获得更好的预后。

Objective To explore and analyze the effect of carboprost tromethamine injection combined with balloon tamponade on postpartum hemorrhage of placenta previa cesarean section.Methods A total of 80 patients with postpartum hemorrhage after placenta previa cesarean section treated in Linqu County People's Hospital of Weifang City,Shandong Province from March 2020 to August 2022 were selected as the study objects purposively,and were divided into two groups with 40 cases in each group according to different treatment method.The control group was treated with oxytocin combined with carboprost tromethamine injection,and the observation group was treated with balloon tamponade.The clinical efficacy,operation time,first menstrual time,white blood cell count,serum C-reactive protein,blood loss,hospital stay,blood transfusion rate and hysterectomy rate were compared between the two groups.Results The total clinical effective rate of observation group was 95.00%,which was higher than that of control group(77.50%),and the difference was statistically significant(χ^(2)=5.165,P<0.05).Operation time,first menstrual time,white blood cell count,serum C-reactive protein level,intraoperative blood loss,2 h postpartum blood loss,24 h postpartum blood loss and hospital stay in the observation group were better than those in the control group,the differences were statistically significant(all P<0.05).Conclusion Carboprost tromethamine injection combined with balloon tamponade in the treatment of postpartum hemorrhage of placenta previa cesarean section can obtain better clinical efficacy,better performance of perioperative indicators,and reduce the blood transfusion rate and hysterectomy rate,so as to obtain better prognosis.