抗生素降阶梯治疗重症肺炎的临床效果分析

Clinical Effect Analysis of Antibiotic Downgrading Therapy for Severe Pneumonia

目的分析抗生素降阶梯治疗对重症肺炎的治疗效果。方法选取2020年1月—2023年1月本院纳入的60例重症肺炎患者作为观察对象,按随机数字表法分对照组、观察组,每组30例。其中,对照组采取单一抗生素治疗,观察组采取抗生素降阶梯疗法,观察患者疾病治疗期间的不良反应、疾病疗效、病症改善时间。结果观察组不良反应率比对照组低,组间差异有统计学意义(P<0.05)。观察组有效率比对照组高,组间差异有统计学意义(P<0.05)。观察组症状改善时间均比对照组短,组间差异有统计学意义(P<0.05)。结论重症肺炎以抗生素降阶梯疗法干预的效果显著,可促进患者病情减轻,该疗法的安全性尚可,可作为重症肺炎的治疗方案。

Objective To analyze curative effect of antibiotic downgrading therapy for severe pneumonia.Methods The paper chose 60 patients with severe pneumonia admitted to our hospital from January 2020 to January 2023 as observation subjects,and divided them into control group and observation group with random number table method.Control group was treated with single antibiotic treatment,while observation group with antibiotic step-down therapy.Adverse reactions,disease effect,and time for disease improvement during treatment period were observed.Results Incidence of adverse reactions in observation group was lower than control group,P<0.05.Effective rate of observation group was higher than control group,P<0.05.Improvement time of symptoms in observation group was shorter than control group,P<0.05.Conclusion Antibiotic downgrading therapy can achieve significant intervention effect and promote condition alleviation of severe pneumonia patient,with acceptable safety,which can be treatment plan for severe pneumonia.