动态增强MRI定量参数对HIFU治疗子宫肌瘤的评价

Evaluation of Dynamic Enhanced MRI Quantitative Parameters in HIFU Treatment of Uterine Fibroids

目的探讨动态增强MRI定量参数对高强度聚焦超声(HIFU)治疗子宫肌瘤的疗效。方法将2021年1月—2023年5月在本院使用HIFU治疗的60例子宫肌瘤患者作为研究对象,所有患者均实施动态增强MRI(DCE-MRI)检查,测定各定量参数;根据肌瘤体积消融率分为两组,A组消融≥70%(n=37),B组消融<70%(n=23)。结果HIFU治疗后肌瘤体积明显小于治疗前,Ktrans、Kep、Ve、Vp、BF、BV均低于治疗前,组间差异有统计学意义(P<0.05);A组Ktrans、Kep、Ve、BF、BV均低于B组,组间差异有统计学意义(P<0.05),而两组Vp相当,差异无统计学意义(P>0.05)。结论DCE-MRI定量参数在HIFU治疗子宫肌瘤疗效评价中应用价值较高,能通过各参数评估HIFU疗效,为临床后续治疗提供可靠依据。

Objective To explore and evaluate effect of dynamic enhanced MRI quantitative parameters in high-intensity focused ultrasound(HIFU)treatment of uterine fibroids.Methods The paper chose 60 patients with uterine fibroids treated with HIFU in our hospital from January 2021 to May 2023 as study subjects,measured various quantitative parameters based on dynamic contrastenhanced MRI(DCE-MRI),and divided them into two groups according to ablation rate of myoMA volume:group A had ablation≥70%(n=37),and group B had ablation<70%(n=23).Results Volume of fibroids after HIFU treatment was significantly smaller than before treatment,and Ktrans,Kep,Ve,Vp,BF,BV were lower than before treatment(P<0.05).Levels of Ktrans,Kep,Ve,BF,and BV of group A were lower than Group B(P<0.05),while Vp between two groups was equivalent(P>0.05).Conclusion Quantitative parameters of DCE-MRI have high application value in evaluation of curative effect of HIFU for uterine fibroids,can evaluate curative effect of HIFU through various parameters,provide reliable basis for subsequent clinical treatment.