晚期胎盘急性绒毛膜羊膜炎与胎膜早破的相关性研究

Correlation Study between Advanced Placental Acute Chorioamnionitis and Premature Rupture of Membranes

目的探讨晚期胎盘急性绒毛膜羊膜炎(CAM)和胎膜早破(PROM)的相关性。方法收集2022年1—12月在本院分娩的产妇完整胎盘送病理检查,依据检查结果分为正常妊娠分娩产妇50例为对照组,出现胎膜早破分娩产妇105例为观察组,在孕妇分娩时取胎盘组织,进行病理检查,观察急性CAM发生率,对比两组产妇一般资料(年龄、流产史、产次、妊娠期高血压、妊娠期糖尿病)。结果对照组发生急性CAM为6例(12.00%),观察组发生急性CAM为65例(61.90%),观察组发生急性CAM显著高于对照组,对比差异具有统计学意义(P<0.05)。观察组流产人数、急性CAM人数及妊娠期高血压、妊娠期糖尿病人数均高于对照组,对比差异具有统计学意义(P<0.05)。logistics多因素回归分析表明,产妇PROM发生的危险因素为CAM和具有流产史(P<0.05)。结论晚期胎盘CAM和PROM具有相关性,PROM产妇急性CAM的发生率升高,急性CAM是PROM发生的危险因素。

Objective To explore correlation between advanced placental acute chorioamnionitis(CAM)and premature rupture of membranes(PROM).Methods The paper collected complete placentas delivered in the third trimester of pregnancy from January 2022 to December 2022 for pathological examination,and divided 50 pregnant women into control group and 105 pregnant women with premature rupture of membranes into observation group according to examination results.Placenta tissue of pregnant women was taken during delivery for pathological examination,incidence of acute CAM was observed.General data between two groups of pregnant women(age,abortion history,birth times,pregnancy hypertension,pregnancy diabetes)were compared.Results There were 6 cases(12.00%)of acute CAM in control group and 65 cases(61.90%)in observation group.Incidence of acute CAM in observation group was significantly higher than control group(P<0.05),and difference was statistically significant.Number of abortions,acute CAM,pregnancy induced hypertension and pregnancy induced diabetes in observation group was higher than control group(P<0.05).Logistic multiple regression analysis showed risk factors for maternal PROM were CAM and history of miscarriage(P<0.05).Conclusion There is correlation between advanced placental CAM and PROM,and PROM mothers have high incidence of acute CAM.Acute CAM is a risk factor for incidence of PROM.