CT引导下硬化剂联合术中体表定位在外周性早期肺腺癌患者手术治疗中的应用分析

Application Analysis of CT-guided Sclerotherapy Combined with Intraoperative Body Surface Localization in the Surgical Treatment of Patients with Early Peripheral Lung Adenocarcinoma

目的:探讨CT引导下硬化剂联合术中体表定位在外周性早期肺腺癌患者手术治疗中的应用。方法:选取2020年6月—2024年3月在赣州市立医院行胸腔镜肺楔形切除术治疗的外周性早期肺腺癌患者92例,按照手术定位方法不同分为两组,其中对照组(n=45)采用术中体表定位,联合组(n=47)联合CT引导下硬化剂定位。比较两组定位效果,肺功能指标及并发症发生情况。结果:联合组定位成功率高于对照组,定位探查时间、手术时间均较对照组更短、术中出血量较对照组更少,差异均有统计学意义(P<0.05)。术后2周,两组用力肺活量(FVC)、呼气流量峰值(PEF)、第1秒用力呼气容积占预计值百分比(FEV_(1)%pred)水平均较术前降低,但联合组各项指标均高于同期对照组,差异均有统计学意义(P<0.05)。联合组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:CT引导下硬化剂联合术中体表定位能提高外周性早期肺腺癌患者手术定位效果,缩短手术操作时间并减轻肺组织损伤,且能降低并发症发生率。

Objective:To investigate the application of CT-guided sclerotherapy combined with intraoperative body surface localization in the surgical treatment of patients with early peripheral lung adenocarcinoma.Method:A total of 92 patients with early peripheral lung adenocarcinoma who underwent thoracoscopic wedge resection of the lung in Ganzhou Municipal Hospital from June 2020 to March 2024 were selected and divided into two groups according to different surgical localization methods.The control group(n=45)underwent intraoperative body surface localization,and the combined group(n=47)combined with CT-guided sclerotherapy localization.The localization effect,pulmonary function indexes and complications were compared between the two groups.Result:The localization success rate of the combined group was higher than that of the control group,and the localization exploration time and operation time were shorter than those of the control group,and intraoperative blood loss was less than that of the control group,the differences were statistically significant(P<0.05).At 2 weeks after operation,the levels of forced vital capacity(FVC),peak expiratory flow(PEF)and the percentage of forced expiratory volume in the first second to the expected value(FEV_(1)%pred)in two groups were lower than those before surgery,but all indexes in the combined group were higher than those in the control group,with statistical significance(P<0.05).The complication rate of combined group was lower than that of control group,the difference was statistically significant(P<0.05).Conclusion:CT-guided sclerotherapy combined with intraoperative body surface localization can improve the surgical localization effect of patients with early peripheral lung adenocarcinoma,shorten the operation time,reduce lung tissue injury,and reduce the incidence of complications.