地佐辛与瑞芬太尼用于经腹直肠癌根治术中麻醉镇痛的效果分析

Effect of Dezocine and Remifentanil on Anesthesia and Analgesia During Radical Resection of Abdominal Rectal Cancer

目的分析在经腹直肠癌根治术中应用地佐辛和瑞芬太尼的麻醉效果。方法随机选取单县中心医院麻醉科于2022年1月—2023年10月进行手术的80例直肠癌患者为研究对象,均使用随机数表法方式分成对照组(瑞芬太尼麻醉)和研究组(地佐辛麻醉),每组40例,对比两组麻醉后的临床效果、麻醉时期呼吸循环相关指标。结果研究组患者的收缩压、二氧化碳分压等呼吸循环功能在麻醉前、麻醉时、手术时、苏醒时与对照组相比,差异无统计学意义(P均>0.05);两组手术时氧分压比较,差异有统计学意义(P<0.05)。两组手术时间比,较差异无统计学意义(P>0.05)。研究组自主恢复呼吸时间(3.21±1.02)min、苏醒时间(8.56±1.24)min以及拔管时间(11.26±1.02)min均短于对照组,差异有统计学意义(t=5.027、3.872、2.617,P均<0.05)。研究组在麻醉时及手术结束后平均动脉压、心率指标水平均优于对照组,差异有统计学意义(P均<0.05)。结论相比较瑞芬太尼维持麻醉,地佐辛麻醉效果更好,可以降低患者围术期疼痛程度,改善血流动力学指标。

Objective The anesthetic effects of dezocine and remifentanil in transabdominal radical resection of ab-dominal rectal cancer were analyzed.Methods A total of 80 patients with rectal cancer who underwent surgery in the Department of Anesthesiology,Shanxian Central Hospital from January 2022 to October 2023 were randomly selected as the research objects.They were divided into control group(remifentanil anesthesia)and study group(dezocine anes-thesia)by random number table method,with 40 cases in each group.The clinical effects after anesthesia and the re-lated indexes of respiration and circulation during anesthesia were compared between the two groups.Results There were no statistically significant difference in systolic blood pressure,carbon dioxide partial pressure and other respira-tory and circulatory functions between the study group and the control group before anesthesia,during anesthesia,dur-ing surgery and during recovery(all P>0.05).There was statistically significant difference in oxygen partial pressure between the two groups(P<0.05).There was no significant difference in operation time between the two groups(P>0.05).The spontaneous recovery breathing time was(3.21±1.02)min,recovery time was(8.56±1.24)min and extuba-tion time was(11.26±1.02)min in the study group,which were shorter than those in the control group,and the differ-ences were statistically significant(t=5.027,3.872,2.617,all P<0.05).The mean arterial pressure and heart rate of the study group were better than those of the control group at the time of anesthesia and after the operation,and the differences were statistically significant(all P<0.05).Conclusion Compared with remifentanil,dezocine has better an-esthetic effect,which can reduce the degree of perioperative pain and improve hemodynamic indexes.