腹腔镜阑尾切除术治疗急性阑尾炎的临床效果分析

Analysis on Clinical Effect of Laparoscopic Appendectomy in Treatment of Acute Appendicitis

目的:分析腹腔镜阑尾切除术治疗急性阑尾炎的临床效果。方法:选取2021年5月—2023年9月于兰州市第一人民医院普外科进行手术治疗的140例急性阑尾炎患者作为研究对象,随机分为观察组和对照组,各70例。对照组实施常规开腹阑尾切除术,观察组实施腹腔镜阑尾切除术。比较两组治疗效果。结果:观察组手术时间、住院时间短于对照组,首次下床活动时间、恢复肛门排气时间早于对照组,术中出血量少于对照组,差异有统计学意义(P<0.001)。观察组并发症总发生率低于对照组,差异有统计学意义(P=0.009)。术后3 d,两组C反应蛋白、血清淀粉样蛋白、降钙素原、肿瘤坏死因子-α水平低于术前,且观察组低于对照组,差异有统计学意义(P<0.05)。术后1周,两组生理功能、精神健康、社会功能、情感职能评分高于术前,且观察组高于对照组,差异有统计学意义(P<0.05)。结论:腹腔镜阑尾切除术治疗急性阑尾炎的临床效果显著,可缩短手术时间,减少术中出血量,促进患者康复,减少并发症,减轻炎性反应,提高患者生活质量。

Objective:To analyze the clinical effect of laparoscopic appendectomy in the treatment of acute appendicitis.Methods:A total of 140 patients with acute appendicitis who underwent surgical treatment in the General Surgery Department at the First People's Hospital of Lanzhou City from May 2021 to September 2023 were selected as the study subjects.They were randomly di⁃vided into observation group and control group,with 70 cases in each group.The control group underwent conventional open ap⁃pendectomy,and the observation group underwent laparoscopic appendectomy.The treatment effects were compared between the two groups.Results:The operation time and the length of hospital stay in the observation group were shorter than those in the con⁃trol group,the time of first ambulation and the time of resuming anal exhaust in the observation group were earlier than those in the control group,the intraoperative blood loss in the observation group was less than that in the control group,and the difference was statistically significant(P<0.001).The total incidence of complications in the observation group was lower than that in the con⁃trol group,and the difference was statistically significant(P=0.009).On 3 d after operation,the levels of C-reactive protein,serum amyloid,procalcitonin and tumor necrosis factor-αin the two groups were lower than those before operation,the levels in the ob⁃servation group were lower than those in the control group,and the difference was statistically significant(P<0.05).At 1 week after operation,the scores of physiological function,mental health,social function and emotional function in the two groups were higher than those before operation,the scores in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).Conclusion:Laparoscopic appendectomy in the treatment of acute appendicitis has significant clinical effects,and can shorten the operation time,reduce the intraoperative blood loss,promote the recovery of patients,reduce complications,relieve inflammatory reaction,and improve the quality of life of patients.