河北省部分地区2型糖尿病患者血脂异常流行状况及影响因素

Prevalence and influencing factors of dyslipidemia in patients with type 2 diabetes mellitus in some areas of Hebei province

目的 了解河北省2型糖尿病(T2DM)患者血脂异常的患病现状及影响因素。方法 利用河北省糖尿病并发症研究数据,分析4个区县1 844例≥18岁T2DM患者血脂异常的患病情况,采用多因素Logistic回归分析模型探讨T2DM患者血脂异常患病的相关影响因素。结果 1 844例T2DM患者中,1 112例T2DM患者血脂异常,血脂异常患病率为60.7%。TC异常、TG异常、HDL-C异常和LDL-C异常患病率分别是26.5%、8.3%、25.4%和9.8%。多因素Logistic回归模型分析结果显示,城市糖尿病患者(OR=0.766,95%CI:0.621~0.944,P<0.001)血脂异常患病率较低,中心型肥胖(OR=15.476,95%CI:11.111~21.556,P<0.001)、高血压(OR=1.543,95%CI:1.244~1.914,P<0.001)人群血脂异常患病风险较高。结论 河北省部分地区T2DM患者血脂异常患病率较高,T2DM患者应重点关注血脂水平。

Objective To understand the current prevalence and influencing factors of dyslipidemia in patients with type 2 diabetes mellitus(T2DM) in Hebei Province.Methods Using data from the Hebei Diabetes Complications Study,we analyzed the prevalence of dyslipidemia in 1,844 T2DM patients aged 18 years and older in four districts and counties in Hebei Province,and a multifactorial logistic regression analysis model was performed to explore the factors associated with the prevalence of dyslipidemia in T2DM patients.Results Among 1,844 T2DM patients,the prevalence of dyslipidemia was 60.7%(1,112/1,844).The abnormal prevalence of total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C) were 26.5%,8.3%,25.4% and 9.8%,respectively.The results of multifactorial logistic regression model analysis showed that the prevalence of dyslipidemia was significantly lower in urban diabetic patients(OR=0.766,95% CI:0.621-0.944,P<0.001),and the abnormal prevalence of central obesity(OR=15.476,95% CI:11.111-21.556,P<0.001),hypertension(OR= 1.543,95% CI:1.244-1.914,P<0.001) were at higher risk of dyslipidemia.Conclusion The prevalence of dyslipidemia is significantly higher in patients with T2DM in some areas of Hebei province,and patients with T2DM should focus on lipid levels.