针刺治疗偏头痛的机制研究进展

Research Progress on Mechanism of Acupuncture Treatment for Migraine

偏头痛是一种常见的失能性原发性头痛,严重影响患者的工作及生活。针刺对偏头痛预防性治疗及急性期治疗在临床上被证实确有疗效,诸多学者通过临床研究及动物实验对针刺治疗偏头痛的机制进行了不同角度的探索。得出针刺主要是调节三叉神经血管通路相关物质水平、改善脑血管血流速度、抑制c-fos基因及蛋白水平表、调节脑功能网络的异常连接等作用起到治疗偏头痛的结论。

Migraine is a common incapacitated primary headache, which seriously affects the patient's work and life. Acupuncture has been clinically proven to be effective in the preventive treatment and acute phase treatment of migraine. Many scholars have explored the mechanism of acupuncture in the treatment of migraine from different angles through clinical studies and animal experiments. It is concluded that acupuncture can regulate the levels of trigeminal vascular pathway related substances, improve cerebral blood flow velocity, inhibit c-fos gene and protein level and regulate the abnormal connection of brain functional network to treat migraine.