木质素生物合成翻译后修饰调控研究进展

Advances on the Post-translational Modifications Regulating of Lignin Biosynthesis

蛋白质翻译后修饰(post-translational modifications,PTMs)在植物生长发育过程中具有十分重要的作用,它们通过调节蛋白质的结构、稳定性以及活性,从而影响植物的生长发育以及响应环境胁迫的能力。木质素生物合成途径及其上游转录调控机制目前已研究得较为清楚,但翻译后修饰研究较少。综述了木质素生物合成翻译后修饰调控的最新研究进展,重点介绍了磷酸化、泛素化、糖基化和S-亚硝基化4类重要的翻译后修饰对木质素合成关键酶和转录因子的调控机制,旨在深化对木质素生物合成调控机理的认知,并为深入理解植物木质素合成的精准时空调控机制提供参考和启发。

Protein post-translational modifications(PTMs)play a crucial role in plant growth and development.They significantly impact plant growth,development,and the ability to adapt to environmental stresses by fine-tuning the structure,stability,and activity of proteins.While the lignin biosynthetic pathway and its upstream transcriptional regulation have been extensively investigated,research on PTMs in this context remains relatively limited.This review summarized the latest advancements in understanding the regulation of lignin biosynthesis by PTMs,particularly focusing on four significant types:phosphorylation,ubiquitination,glycosylation,and S-nitrosylation.It highlighted the regulatory mechanisms of these PTMs on key enzymes and transcription factors involved in lignin biosynthesis,aiming to enhance our comprehension of the regulatory networks governing lignin biosynthesis and provide valuable insights and references for the precise spatiotemporal modulation of this crucial process in plants.