摘要
The brain,the most vital and intricate organ in the human body,governs neural activities.Homeostasis within the brain is protected by the blood–brain barrier(BBB),a unique and highly regulated semi-permeable membrane[1].Due to the BBB obstruction,traditional drug delivery methods,such as oral administration or intravenous injection,often fail to efficiently deliver drugs to the brain[2].
作者
徐臆茹
丁涛
陈信良
Yiru Xu;Tao Ding;Xinliang Chen(The International Peace Maternity and Child Health Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200030,China;Shanghai Key Laboratory of Embryo Original Diseases,Shanghai 200030,China;Department of Orthopaedics,Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases,Shanghai Institute of Traumatology and Orthopaedics,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China)
基金
supported by the National Natural Science Foundation of China(8237060413)
the Shanghai Special Project on Aging and Women’s and Children’s Health Research(2020YJZX0132)。
