2017-2022年山东省德州市德城区9~45岁女性HPV疫苗接种情况分析

Analysis of HPV vaccination coverage among women aged 9−45 years in Decheng District,Dezhou City,Shandong Province,2017−2022

目的 了解山东省德州市德城区9~45岁女性人乳头瘤病毒(human papilloma virus,HPV)疫苗接种情况,为下一步加速推动消除宫颈癌行动计划提供数据支持。方法 利用山东省免疫规划信息系统收集2017-2022年山东省德州市德城区适龄女性二价、四价、九价HPV疫苗接种信息,分析德城区不同年份、不同年龄段和不同地区适龄女性HPV疫苗接种情况。结果 2017-2022年德城区适龄女性共接种HPV疫苗83 791剂次,其中接种二价HPV疫苗34 345剂次,占总剂次数的40.99%,接种剂次数逐年上升。德城区适龄女性共接种HPV疫苗第一剂32 927剂次,适龄女性人口接种覆盖率为19.02%。其中,9~15岁女性接种覆盖率最低(2.08%),16~26岁女性接种覆盖率最高(24.31%),两组比较差异有统计学意义(χ^(2)=44.20,P<0.05)。城区、城乡结合部、农村适龄女性接种覆盖率分别为40.55%、6.25%和4.90%,差异有统计学意义(χ^(2)=255.14,P<0.05)。完成HPV疫苗全程接种的人数为21 806人,全程接种率为12.60%。结论 德城区9~45岁适龄女性HPV疫苗总体接种率偏低,应继续加强宫颈癌疾病和HPV疫苗的科普知识宣传及健康教育,提高德城区女性HPV疫苗接种率。9~15岁女性、农村地区和城乡结合部适龄女性接种率较低,应作为健康教育的重点人群和制定政策时重点关注的对象。

Objective To understand the vaccination coverage of human papillomavirus(HPV)among women aged 9-45 years in Decheng District,Dezhou City,Shandong Province and to provide data support for accelerating the elimination of cervical cancer.Methods Utilizing the immunization planning information system of Shandong Province,vaccination information for bivalent,quadrivalent,and 9-valent HPV vaccines among age-appropriate women in Decheng District,Dezhou City,Shandong Province from 2017 to 2022 was collected and analyzed.This information was used to assess the HPV vaccination status among age-appropriate women in different years,age groups,and regions of Decheng District.Results A total of 83791 doses of HPV vaccine were administered in Decheng District from 2017 to 2022,with 32927 doses being the first dose.The vaccination coverage rate among age-appropriate women was 19.02%.The vaccination coverage rate was highest among women aged 16-26 years(24.31%),while it was the lowest among women aged 9-15 years(2.08%).The vaccination coverage rate of age-appropriate women in urban areas was 40.55%,compared to 6.25%in urban-rural fringes and 4.90%in rural areas.The number of women who completed the full vaccination was 21806,and the full vaccination rate was 12.60%.Conclusion The overall HPV vaccination rate among women aged 9-45 years in Decheng District is low.There is a need to continue strengthening public awareness on cervical cancer and HPV vaccines,as well as enhancing health education,to increase the HPV vaccination rate among women in Decheng District.Women aged 9-15 years and women living in rural areas and urban-rural fringes exhibit lower vaccination rates and should be prioritized as key targets for health education and policy interventions.