基于微生物的稀土材料制备

Microbial-driven fabrication of rare earth materials

稀土元素(REEs)作为现代高科技产业发展的关键原材料,在多个前沿领域具有广泛应用.然而,由于稀土元素分布相对分散,其提取往往伴随着环境退化.此外,稀土元素的相似化学性质导致了分离过程中的高能耗和过度污染排放.为了实现稀土的绿色发展和高效资源利用,通过合成生物学技术构建了工程稀土微生物.此外,我们建立了工程稀土微生物合成平台,实现了原位合成高附加值的稀土生物材料,推动了临床转化研究和应用的进展.本文综述了稀土微生物的合理设计、高价值稀土生物材料的合成及其应用.最后,简要讨论了该领域的未来研究和发展前景.

Rare earth elements(REEs)are essential raw materials vital for the advancement of modern high-tech industries.However,their extraction often leads to environmental concerns.The similar chemical properties of REEs contribute to high energy consumption and significant pollution emissions during the separation process.To address these challenges and promote sustainable development and efficient resource utilization,synthetic biology techniques have been leveraged to engineer microorganisms for rare earth fabrication.Establishing an engineered microorganism manufacture platform allows for the in-situ synthesis of high-value rare earth biomaterials.This innovation not only supports clinical translational research but also enhances applications in cutting-edge fields.This article offers a comprehensive review of the rational construction of rare earth cell factories,the synthesis of high-value rare earth biomaterials,and their diverse applications in high-tech industries.Moreover,it examines the perspectives and challenges within the domain of lanthanide materials fabrication using microbial systems.