同位素稀释-高分辨气相色谱/高分辨质谱法测定鱼油中总多氯联苯

Determination of Total Congeners in Fish Oil:Isotope Dilution HRGC/HRMS

多氯联苯是主要的持久性有机污染物分类之一,总多氯联苯是IFOS五星认证中一项重要限制性指标。本文建立了一种同位素稀释-高分辨气相色谱/高分辨质谱测定鱼油中209种多氯联苯总含量的分析方法。鱼油样品经正己烷萃取后,经过浓缩、净化,经过同位素标识过程,使用高分辨气相色谱/高分辨质谱(HRGC-HRMS)对目标物进行测定。鱼油中总多氯联苯的检出限为1.4 ng/g,定量下限为5.4 ng/g。

PCBs is one major category of Persistent Organic Pollutants(POPs),and total 209 Congeners is restrictive indicator for IFOS five-star authentication.A method had been developed for determination of total 209 Congeners in fish oil by isotope dilution HRGC/HRMS.After fish oil samples were extracted with hexane,the extraction solution is concentrated,purified,and subjected to isotope labeling.The target substance is determined using HRGC-HRMS.The method detection limit is 1.4 ng/g,and minimum quantitative detection limit is 5.4 ng/g.