三路径激素联合应用治疗全聋型突发性聋的疗效分析

目的 观察三路径激素联合应用治疗全聋型突发性聋的疗效。方法 选择2020年1月至2022年12月全聋型突发性聋患者96例,随机分为观察组与对照组,对照组予地塞米松静脉滴注及常规治疗。观察组在此基础上加用鼓室和耳后地塞米松注射,共治疗10 d。结果 对照组患者听力改善22例,有效率45.83%,观察组改善30例,有效率62.50%。治疗前对照组与观察组纯音听阈均值分别为(95.3±13.2)d B HL和(96.1±13.1)d B HL,治疗后分别为(63.2±17.1)d B HL和(52.8±16.8)d B HL,观察组治疗效果优于对照组(P<0.05)。两组耳鸣、眩晕、耳闷等症状改善率差异无统计学意义(P>0.05)。结论 早期三路径激素治疗全聋型突发性聋可有效提高听力恢复,值得临床推广。

Objective To observe the therapeutic effect of three pathway hormone therapy on sudden deafness with total deafness.Methods 96 patients with sudden sensorineural hearing loss from January 2020 to December 2022 were selected and randomly divided into an observation group and a control group.The control group received intravenous dexamethasone infusion and conventional treatment.On this basis,the observation group received additional injections of dexamethasone in the tympanic cavity a nd behind the ear fo r a total of 10 days of treatmen t.Results 22 patients in the control group show ed improvement in hearing,w ith an effective rate of 45.83%,while 30 patients in the observation group showed improvement,with an effective rate of 62.50%.The mean pure tone hearing thresholds of the control group and the observation group before treatment were(95.3±13.2)dB HL and(96.1±13.1)dB HL,respectively.After the treatment,they were(63.2±17.1)dB HL and(52.8±16.8)dB HL,respectively.The treatment effect of the observation group was better than that of the control group(P<0.05).There was no statistically significant difference in the improvement rate of symptoms such as tinnitus,dizziness,and ear tightness between the two groups(P>0.05).Conclusion Early three pathway hormone therapy for sudden deafness can effectively improve hearing recovery and is worthy of clinical promotion.