2015—2019年四川省肿瘤登记地区胃癌发病与死亡变化趋势分析

Trends in Incidence and Mortality of Gastric Cancer in Sichuan Cancer Registration Areas from 2015 to 2019

[目的]分析2015—2019年四川省肿瘤登记地区胃癌发病与死亡变化趋势。[方法]通过“中国肿瘤登记平台”收集四川省2015—2019年肿瘤登记地区数据质量符合要求的胃癌发病与死亡资料,计算累计发病(死亡)数、粗发病(死亡)率、中标发病(死亡)率、世标发病(死亡)率等指标,描述胃癌发病与死亡特征。采用Joinpoint Regression Program 4.9.1.0软件计算平均年度变化百分比(average annual percentage change,AAPC),分析发病与死亡变化趋势。[结果]2015—2019年间四川省肿瘤登记地区累计报告胃癌发病52016例,粗发病率为23.31/10万,中标发病率为13.04/10万;报告死亡40772例,粗死亡率为18.27/10万,中标死亡率为9.91/10万;粗发病(死亡)率、中标发病(死亡)率、世标发病(死亡)率均呈明显下降趋势(P均<0.05)。2015—2019年间农村地区胃癌发病(死亡)率明显高于城市居民(中标发病率:14.30/10万vs 11.02/10万;中标死亡率:10.90/10万vs 8.31/10万),且呈明显下降趋势(P<0.05)。2015—2019年间男性胃癌中标发病(死亡)率均明显高于女性(中标发病率:18.44/10万vs7.62/10万;中标死亡率:14.27/10万vs 5.56/10万),男女性中标发病(死亡)率均呈明显下降趋势(P均<0.05)。2015—2019年间四川省肿瘤登记地区胃癌年龄别发病与死亡率在0~44岁处于较低水平,45岁以后迅速上升,分别于80~84岁与85岁及以上年龄组达到高峰。[结论]2015—2019年四川省肿瘤登记地区胃癌发病和死亡水平虽然低于全国水平并呈下降趋势,但胃癌发病和死亡的绝对数量仍然较高,存在性别和地区差异。应采取胃癌综合防控策略,重点关注中老年人、男性及农村居民。

[Purpose]To analyze the trend in incidence and mortality of gastric cancer in Sichuan cancer registration areas from 2015 to 2019.[Methods]The incidence and mortality data of gastric cancer in Sichuan cancer registries from 2015 to 2019 were derived from the China Cancer Registration Platform.The accumulate incidence and mortality,crude incidence and mortality,the agestandardized incidence and mortality by Chinese(ASIRC,ASMRC)and world(ASIRW,ASMRW)standard population were calculated to describe the incidence and mortality characteristics of gastric cancer.The average annual percentage change(AAPC)of gastric cancer was calculated using Joinpoint Regression Program 4.9.1.0 software to analyze the trends of gastric cancer.[Results]From 2015 to 2019,a total of 52016 cases of gastric cancer were reported in cancer registration areas of Sichuan Province,the crude incidence of gastric cancer was 23.31/105,the ASIRC was 13.04/105;a total of 40772 deaths were reported,the crude mortality rate was 18.27/105,and ASMRC was 9.91/105.The crude rate,ASIRC and ASMRC,ASIRW and ASMRW all showed a significant downward trend(all P<0.05).From 2015 to 2019,the incidence(mortality)rate of gastric cancer in rural areas was significantly greater than that of urban residents(ASIRC:14.30/105 vs 11.02/105;ASMRC:10.90/105 vs 8.31/105),and showed a significant downward trend(P<0.05).From 2015 to 2019,the incidence(mortality)of gastric cancer of men was significantly higher than that of women(ASIRC:18.44/105 vs 7.62/105;ASMRC:14.27/105 vs 5.56/105),and the incidence(mortality)of both men and women showed a significant downward trend(all P<0.05).From 2015 to 2019,the age-specific incidence and mortality of gastric cancer in Sichuan was at a low level between 0 and 44 years old,and increased rapidly after 45 years old,reaching the peak at the age group of 80~84 and 85 years old and above,respectively.[Conclusion]From 2015 to 2019,although the incidence and mortality level of gastric cancer in the cancer registration areas of Sichuan Province was lower than the national level and showed a downward trend,the absolute number of gastric cancer incidence and deaths was still high,and there were gender and regional differences.In the future,comprehensive prevention and control strategies should be adopted,focusing on middle-aged and elderly people,men and rural residents.