痹祺胶囊联合针刺治疗气滞血瘀型神经根型颈椎病的疗效评价

Efficacy evaluation of Biqi Capsules combined with acupuncture in treatment of cervical spondylotic radiculopathy with qi stagnation and blood stasis

目的评价口服痹祺胶囊联合针刺治疗对气滞血瘀型神经根型颈椎病的临床疗效。方法选取60例气滞血瘀型神经根型颈椎病患者,随机分为治疗组和对照组,两组各30例。对照组仅给予针刺治疗,1次/d,留针30 min;治疗组在针刺治疗的基础上,口服痹祺胶囊,4粒/次,2次/d;两组患者均治疗2周。观察两组的临床疗效及治疗前和治疗结束后2周、4周的疼痛视觉模拟评分(visual analogue score,VAS)、颈椎功能障碍指数(neck disability index,NDI)、中医证候积分、颈椎活动度。结果60例患者中共有3例脱落,最终纳入57例。治疗结束后2周,两组总有效率较接近(治疗组96.4%,对照组89.7%),而治疗结束后4周,治疗组总有效率(92.9%)显著优于对照组(65.5%)(P<0.05)。治疗前,两组VAS评分无明显差异(P>0.05),治疗结束后2周和4周两组患者的VAS评分均低于治疗前(P<0.05),且治疗组VAS评分明显低于对照组(P<0.05)。治疗前,两组NDI无明显差异(P>0.05),治疗结束后2周和4周两组患者的NDI均低于治疗前(P<0.05),且治疗组NDI指数明显低于对照组(P<0.05)。治疗前,两组中医证候积分无明显差异(P>0.05),治疗结束后2周和4周两组患者的中医证候积分均低于治疗前(P<0.05),且治疗组中医证候积分明显低于对照组(P<0.05)。治疗前,两组颈椎活动度无明显差异(P>0.05),治疗结束后2周和4周两组患者的颈椎活动度均高于治疗前(P<0.05),且治疗组颈椎活动度明显高于对照组(P<0.05)。结论采用痹祺胶囊联合针刺治疗气滞血瘀型神经根型颈椎病临床疗效显著,改善颈椎功能更明显,疗效更加稳定持久。

Objective To evaluate the therapeutic effect of oral Biqi Capsules(痹祺胶囊) combined with acupuncture on cervical spondylotic radiculopathy with qi stagnation and blood stasis.Methods Sixty patients with cervical spondylotic radiculopathy of qi stagnation and blood stasis sympotom were selected and randomly divided into a treatment group and a control group,with 30 cases in each group.The control group was only given acupuncture treatment,once per day,with needle retention for 30 min;On the basis of acupuncture treatment,the treatment group took orally Biqi Capsules,four capsules per time,two times per day;Both groups of patients were treated for two weeks.The visual analog score(VAS),neck disability index(NDI),traditional Chinese medicine syndrome score,and cervical mobility of the two groups before treatment,two weeks,and four weeks after treatment were observed.Results A total of three out of the 60 patients included in the study fell out,and a total of 57 patients were included in the analysis.After two weeks of treatment,the effective rates of the two groups were relatively close(96.4% in the treatment group and 89.7% in the control group),while after four weeks of treatment,the effective rate of the treatment group(92.9%) was better than that of the control group(65.5%)(P < 0.05).Before treatment,there was no significant difference in VAS scores between the two groups(P > 0.05).After two and four weeks of treatment,the VAS scores of both groups of patients were lower than before treatment(P < 0.05),and the VAS scores of the treatment group were lower than those of the control group(P < 0.05).Before treatment,there was no significant difference in the NDI index between the two groups(P > 0.05).After two and four weeks of treatment,the NDI index of both groups of patients was lower than before treatment(P < 0.05),and the NDI index of the treatment group was lower than that of the control group(P < 0.05).Before treatment,there was no significant difference in the TCM syndrome scores between the two groups(P > 0.05).After two and four weeks of treatment,the TCM syndrome scores of the two groups of patients were lower than before treatment(P < 0.05).The TCM syndrome scores of the treatment group were lower than those of the control group(P < 0.05).Before treatment,there was no significant difference in cervical mobility between the two groups(P > 0.05).After two and four weeks of treatment,the cervical mobility of both groups of patients was higher than before treatment(P < 0.05),and the cervical mobility of the treatment group was higher than that of the control group(P < 0.05).Conclusion The clinical efficacy of Biqi Capsules combined with acupuncture in treatment of cervical spondylotic radiculopathy with qi stagnation and blood stasis type is significant,with more obvious improvement of cervical spine function,and stable and lasting curative effects.