经皮冠状动脉介入术后早期康复训练频率对急性心肌梗死患者临床指标的影响

The Effect of Early Rehabilitation Training Frequency after Percutaneous Coronary Intervention on Clinical Indicators in Patients with Acute Myocardial Infarction

目的:探讨经皮冠状动脉介入(PCI)术后早期康复训练频率对于急性心肌梗死(AMI)患者临床指标的影响。方法:选取2023年1月至2024年1月在郑州市第七人民医院接受PCI治疗的196例AMI患者纳入本研究,根据患者PCI术后早期康复训练频率将入选患者划分为常规组与高频组,每组各98例。训练1个月后,比较两组患者心功能指标、活动耐力指标、应激反应指标、肺功能指标。结果:训练后,高频组患者左心室射血分数(LVEF)高于常规组,左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)低于常规组,差异具有统计学意义(P<0.05)。训练后,高频组患者最大运动功率、最大运动时间、6 min步行试验(6MWT)高于常规组,差异具有统计学意义(P<0.05)。训练后,高频组患者血清髓过氧化物酶(MPO)、超敏C反应蛋白(hs-CRP)、可溶性细胞间黏附分子-1(sICAM-1)、核因子κB(NF-κB)水平低于常规组,差异具有统计学意义(P<0.05)。训练后,高频组患者第1秒用力呼气量(FEV1)、用力肺活量(FVC)、呼气流量峰值(PEF)高于常规组,差异具有统计学意义(P<0.05)。结论:PCI术后早期高频率康复训练能够更好地改善AMI患者PCI术后的心肺功能、增强患者活动耐力。

Objective To investigate the effect of early rehabilitation training frequency after percutaneous coronary intervention(PCI)on clinical indexes of patients with acute myocardial infarction(AMI).Methods A total of 196 AMI patients who received PCI treatment in the 7th People's Hospital of Zhengzhou from January 2023 to January 2024 were selected for inclusion in this study.According to the frequency of early rehabilitation training after PCI,the enrolled patients were divided into a conventional group and a high-frequency group,with 98 cases in each group.After 1 month of training,the cardiac function indexes,activity endurance indexes,stress response indexes and lung function indexes were compared between the two groups.Results After training,the left ventricular ejection fractions(LVEF)in the high-frequency group was higher than that in the conventional group,and the left ventricular end diastolic volume(LVEDV)and left ventricular end systolic volume(LVESV)were lower than those in the conventional group,with statistical significance(P<0.05).After training,the maximum exercise power,maximum exercise time and 6-minute walk test(6MWT)in the high-frequency group were higher than those in the conventional group,and the differences were statistically significant(P<0.05).After training,the serum levels of myeloperoxidase(MPO),hypersensitive C-reactive protein(hs-CRP),soluble intercellular cell adhesion molecule-1(SICAM-1)and nuclear factor kappa-B(NF-κB)in the high-frequency group were lower than those in the conventional group,and the differences were statistically significant(P<0.05).After training,the forced expiratory volume in one second(FEV1),forced vital capacity(FVC)and peak expiratory flow(PEF)in the high-frequency group were higher than those in the conventional group,and the differences were statistically significant(P<0.05).Conclusion Early and high frequency rehabilitation training after PCI can better improve the cardiopulmonary function and enhance the activity endurance of AMI patients after PCI.