冠状动脉支架对缺血性心肌病心力衰竭患者心功能的影响

Effect of Coronary Artery Stent on Cardiac Function in Patients with Ischemic Cardiomyopathy and Heart Failure

目的:分析冠状动脉支架对缺血性心肌病(ICM)心力衰竭(HF)患者心功能的影响。方法:选取2022年1月至2023年12月商丘市第一人民医院收治的ICMHF患者88例,随机分为对照组和观察组,各44例。对照组予以常规药物治疗,观察组在对照组常规药物治疗2周后行冠状动脉支架治疗。比较两组患者临床疗效、纽约心脏病协会(NYHA)分级、X线心胸比、心功能指标、运动耐力、不良心血管事件发生情况。结果:观察组患者临床总有效率高于对照组,差异具有统计学意义(P<0.05)。观察组患者NYHA分级优于对照组,差异具有统计学意义(χ^(2)=2.530,P=0.011)。治疗后,观察组患者X线心胸比低于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组患者左心室舒张末期内径(LVEDD)低于对照组,左心室射血分数(LVEF)、6 min步行距离(6MWD)高于对照组,差异具有统计学意义(P<0.05)。观察组患者不良心血管事件总发生率低于对照组,差异具有统计学意义(P<0.05)。结论:冠状动脉支架治疗ICM HF患者,能够提高心功能,增强治疗效果和运动耐力,减少不良心血管事件的发生。

Objective To analyze the effect of coronary artery stent on cardiac function in patients with ischemic cardiomyopathy(ICM)and heart failure(HF).Methods A total of 88 ICMHF patients admitted to the Shangqiu First People's Hospital from January 2022 to December 2023 were randomly divided into a control group and an observation group,with 44 patients in each group.The control group received conventional drug treatment,and the observation group received coronary artery stent after 2 weeks of conventional drug treatment.The clinical efficacy,New York heart association(NYHA)classification,X-ray cardiothoracic ratio,cardiac function index,exercise endurance and adverse cardiovascular events were compared between the two groups.Results The total clinical effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).NYHA classification in the observation group was better than that in the control group,and the difference was statistically significant(χ^(2)=2.530,P=0.011).After treatment,the X-ray cardiothoracic ratio of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).After treatment,left ventricular end diastolic diameter(LVEDD)in the observation group was lower than that in the control group,left ventricular ejection fractions(LVEF)and 6-minute walking distance(6MWD)were higher than those in the control group,the differences were statistically significant(P<0.05).The total incidence of adverse cardiovascular events in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The treatment of ICM HF patients with coronary artery stenting can improve cardiac function,enhance therapeutic effect and exercise endurance,and reduce the occurrence of adverse cardiovascular events.