肺癌患者免疫治疗真实体验的Meta整合

Experience of immunotherapy in patients with lung cancer:a Meta-synthesis

目的:系统评价肺癌患者接受免疫治疗期间的真实体验,为医护人员制定照护方案提供可靠依据。方法:系统检索国内外数据库中关于肺癌患者免疫治疗真实体验的质性研究,检索时限为建库至2023年8月31日。采用JBI质性研究质量评价标准对文献进行质量评价,采用汇集性Meta整合法进行整合。结果:共纳入10篇文献,提炼出54个研究结果,归纳为9个新类别,形成3个整合结果,包括免疫治疗所带来的多重挑战、患者存在多维度需求、积极自我调整并实现角色成长。结论:肺癌免疫治疗患者面临生理、心理及家庭社会等多方面的挑战,医护人员应注意提高患者对治疗的认知程度、动态监测症状变化轨迹并满足其多方面的需求。

Objective:To systematically evaluate the real experience of immunotherapy in patients with lung cancer,so as to provide a reliable basis for medical staff to formulate care plan.Methods:Qualitative studies on the experience of immunotherapy inpatients with lung cancer were searched from CNKI,VIP,Wanfang,SinoMed,PubMed,Web of Science,Cochrane Library,Embase,Scopus,CINAHL,PsycINFO and other databases from the inception of the database to August 31,2023.The JBI qualitative research quality evaluation criteria were used to evaluate the quality of the literature,and the aggregated Meta-synthesis method was used to integrate the results.Results:A total of 10 studies were included,and 54 findings were extracted and summarized into 9 new categories to form 3 integrated results,including multiple challenges brought by immunotherapy,multi-dimensional needs of patients,positive self-adjustment and role growth.Conclusion:Patients with lung cancer immunotherapy are faced with many challenges from physiology,psychology,family and society.Medical staff should pay attention to improving patients'cognition of treatment,dynamically monitoring the symptoms,and meeting their various needs.