伤口造口干预对慢性难愈创面治疗效果、炎症因子影响

Research on the Application of Wound Stoma Intervention Group in theTreatment and Control of Chronic Refractory Wounds

目的探讨分析慢性难愈创面的治疗与控制中伤口造口干预的应用价值。方法选取2022年3月至2023年9月黄河三门峡医院收治的慢性难愈创面患者74例作为观察对象,采取随机数字表格法分组,对照组37例,接受常规皮肤干预管理,观察组37例,在常规管理基础上联合伤口造口干预,观察两组创面治疗情况、疼痛水平、炎症指标情况。结果两组患者各项症状改善、修复准备与患者住院消耗时间比较,观察组均低于对照组(P<0.05)。患者疼痛程度NRS评分干预前组间数据差异无统计学意义(P>0.05);干预后不同时间点疼痛程度NRS评分观察组低于对照组(P<0.05)。炎症指标CRP、IL-1β、TNF-α干预后低于干预前(P<0.05),观察组炎症指标下降更明显(P<0.05)。结论对慢性难愈创面患者开展伤口造口干预,有助于更好地控制病情,促进创面愈合,缩短住院时间,减轻患者疼痛体验,降低机体炎症反应水平。

Objective To explore and analyze the application value of wound stoma intervention in the treatment and control of chronic refractory wounds.Methods In this study,74 patients with chronic refractory wounds admitted to Sanmenxia Hospital of the Yellow River from March 2023 to March 2024 were selected as observation subjects.They were divided by random number table method.37 patients in the control group received routine skin intervention management,and 37 patients in the observation group received wound stoma intervention on the basis of routine management.The wound treatment result,pain level,and inflammation index of the two groups were observed.Results In this study,the time spent on symptom improvement,repair preparation,and hospitalization in the observation group was lower than that in the control group(P<0.05).There was no statistical significance in NRS score between the two groups before intervention(P>0.05).The NRS score at different time points after intervention was lower in the observation group than in the control group(P<0.05).The inflammatory indexes of CRP,IL-1βand TNF-αwere lower after intervention than before intervention(P<0.05).The inflammation indexes in the observation group decreased more significantly than those in the control group decreased(P<0.05).Conclusion Wound stoma intervention for patients with chronic refractory wounds can help patients with better control of their condition,promoting wound healing,shortening hospital stay,reducing patients’pain experience,reducing the level of body inflammation,and improvi ng patients’quality of life.