桑源中药保健食品的组方规律及质量控制分析

Compatibility Rules and Quality Control of Health Food Containing Chinese Medicines Derived from Mulberry

目的:探讨不同桑源中药保健食品的组方规律并分析其质量控制现状。方法:构建桑源中药保健食品数据库,对其保健功能进行统计,运用频数、性味、归经、功效、关联规则等分析主要保健功能组方规律,结合文献分析其质量控制现状。结果:桑源中药保健食品中,以有助于增强免疫力、缓解体力疲劳的桑椹保健食品和有助于维持血糖健康水平的桑叶保健食品为主。在有助于增强免疫力的桑椹保健食品中,代表性组合为桑椹-黄精-黄芪;在缓解体力疲劳的桑椹保健食品中,代表性组合为桑椹-山药-覆盆子;在有助于维持血糖健康水平的桑叶保健食品中,代表性组合为桑叶-玉竹-山药;三类桑源中药保健食品的功效成分/标志性成分均涉及总皂苷、粗多糖、总黄酮。结论:桑源中药保健食品的组方规律基本符合中医理论和现代医学理论,研究可为产品研发提供思路,其质量控制成分的研究有待深入,其中桑白皮、桑枝保健食品开发力度有待增强。

Objective:To explore the compatibility rules of health food containing Chinese medicines derived from mulberry and analyze the quality control status.Methods:A library of health food products containing Chinese medicines derived from mulberry was established.The frequency,nature,taste,meridian tropism,efficacy,and association rules of the Chinese medicines were analyzed to summarize the compatibility rules.The quality control status was analyzed based on the available articles.Results:The health food products containing Chinese medicines derived from mulberry were dominated by the Mori Fructus-based products with the effects of enhancing immunity and relieving physical fatigue and the Mori Folium-based products with the functions of maintaining the blood glucose level.In the Mori Fructus-based health food products for enhancing immunity,the representative combination was Mori Fructus-Polygonati Rhizoma-Astragali Radix.In the Mori Fructus-based health food products for relieving physical fatigue,the representative combination was Mori Fructus-Dioscoreae Rhizoma-Rubi Fructus.In the Mori Folium-based health food products for maintaining the blood glucose level,the representative combination was Mori Folium-Polygonati Odorati Rhizoma-Dioscoreae Rhizoma.The functional components in the three types of products all involved total saponins,crude polysaccharides,and total flavonoids.Conclusion:The compatibility rules of the health food products containing Chinese medicines derived from mulberry basically conforms to the theories of traditional Chinese medicine and modern medicine.The findings can provide ideas for product development.Further research is needed regarding the quality control components,and the development of health food based on Mori Cortex and Mori Ramulus needs to be strengthened.