早期消化道肿瘤患者病变部位及年龄对ESD术后并发症的影响

The Influence of Lesion Location and Age on Postoperative Complications of ESD in Patients with Early Gastrointestinal Tumors

【目的】探讨早期消化道肿瘤患者病变部位及年龄对内镜黏膜下剥离术(ESD)术后并发症的影响。【方法】选取2018年2月至2021年3月本院收治的89例早期消化道肿瘤患者,所有患者均行ESD治疗。统计ESD术后1个月并发症发生情况,分析影响早期消化道肿瘤患者ESD术后发生并发症的因素,分析不同年龄段、不同病变部位患者并发症发生情况。【结果】89例早期消化道肿瘤患者术后1个月有15例(16.85%)出现并发症。Logistic多因素回归分析显示,年龄≥60岁、病变部位在结直肠、长期服用抗血栓药物是影响早期消化道肿瘤患者ESD术后发生并发症的独立因素(P<0.05)。年龄≥60岁患者的并发症发生率高于年龄<60岁患者(P<0.05)。结直肠病变患者并发症发生率高于食管病变患者(P<0.05)。【结论】早期消化道肿瘤患者ESD术后并发症发生风险高,早期消化道肿瘤患者ESD术后并发症与发生病变部位、年龄有关,临床需重点关注老年患者、结肠病变患者。

【Objective】To investigate the influence of lesion location and age on postoperative complications of endoscopic submucosal dissection(ESD)in patients with early gastrointestinal tumors.【Methods】A total of 89 patients with early gastrointestinal tumors admitted to our hospital from February 2018 to March 2021 were selected,and all patients underwent ESD treatment.We collected statistics on the incidence of complications one month after ESD surgery,analyzed the factors that affect the occurrence of complications in patients with early gastrointestinal tumors after ESD surgery,and analyzed the incidence of complications in patients of different age groups and different lesion sites.【Results】Among 89 patients with early gastrointestinal tumors,15 cases(16.85%)developed complications one month after surgery.Logistic multiple regression analysis showed that age≥60 years,location of lesions in the colon,and long-term use of antithrombotic drugs were independent factors affecting the occurrence of complications after ESD surgery in patients with early gastrointestinal tumors(P<0.05).The incidence of complications in patients aged≥60 years is higher than that in patients aged<60 years(P<0.05).The incidence of complications in patients with colorectal lesions was higher than that in patients with esophageal lesions(P<0.05).【Conclusion】Early digestive tract tumor patients have a high risk of postoperative complications after ESD surgery.The postoperative complications of ESD surgery in early digestive tract tumor patients are related to the site of the lesion and age.Clinical attention should focus on elderly patients and patients with colon lesions.