2022年山东省宫颈癌筛查项目结果分析

Analysis of cervical cancer screening project results in Shandong Province 2022

目的了解2022年山东省35~64岁适龄女性宫颈癌及癌前病变的检出情况,为后续开展免费筛查项目及实现消除宫颈癌目标提供依据。方法本研究基于2022年山东省宫颈癌免费筛查项目,选取2022-01-01-2022-12-31间接受宫颈癌免费筛查的女性。研究数据由山东省妇幼保健院汇总,数据来源于各县(市、区)妇幼保健机构季度报表,涵盖宫颈细胞学伯塞斯达系统(TBS)和宫颈病理等检查结果。本研究对筛查数据进行统计分析,并绘制各地市宫颈癌及癌前病变检出率地图。结果本研究共纳入参加山东省宫颈癌免费筛查项目的2887279名女性,结果显示,2022年山东省宫颈癌检出率为14.75/10万(426/2887279),癌前病变检出率为484.89/10万(14000/2887279)。TBS报告显示,山东省宫颈细胞学总体异常检出率为3.27%(94342/2887279),其中不典型鳞状上皮细胞(ASC-US)检出率最高为2.34%(67618/2887279)。威海市宫颈细胞学异常检出率最高为4.57%(1196/26158),东营市阴道镜异常检出率最高为71.28%(995/1396)。结论2022年山东省宫颈癌免费筛查项目取得了显著成效,仍需继续推广宫颈癌筛查工作,加大宫颈癌防治知识的宣传力度,扩大筛查覆盖范围,并鼓励适龄女性接种HPV疫苗。要进一步探索与中国国情相适应的宫颈癌消除策略,以降低宫颈癌的发病率和死亡率,从而提高女性的生存质量。

Objective To investigate the detection rates of cervical cancer and precancerous lesions among women aged 35-64 in Shandong Province in 2022,providing evidence for the implementation of free screening programs and the achievement of cervical cancer eradication targets.Methods This study is based on the cervical cancer screening program provided free of charge by Shandong Province in 2022,focusing on women who participated in the screening between January 1,2022,and December 31,2022.Data were aggregated by the Shandong Provincial Maternal and Child Health Hospital,sourced from quarterly reports submitted by maternal and child health institutions across the various counties(cities,districts),These reports included results from cervical cytology using the Bethesda System(TBS)and cervical pathology examinations.This research involved a statistical analysis of the screening data and the creation of a map depicting the detection rates of cervical cancer and its precancerous lesions across different cities.Results The study included 2887279women who participated in the free cervical cancer screening program in Shandong Province.The results indicated a cervical cancer detection rate of 14.75 per 100000(426/2887279)and a precancerous lesion detection rate of 484.89 per 100000(14000/2887279).TBS cervical cytology results showed an overall abnormal detection rate of 3.27%(94342/2887279)within the province,with the highest incidence of atypical squamous cells of undetermined significance(ASC-US)at2.34%(67618/2887279).Weihai City had the highest rate of abnormal cervical cytology findings at 4.57%(1196/26158),while Dongying City had the highest colposcopy abnormality rate at 71.28%(995/1396).Conclusions The cervical cancer screening program in Shandong Province achieved significant results in 2022.However,there is still a need to continue promoting cervical cancer screening efforts,enhance the dissemination of knowledge about cervical cancer prevention,expand the scope of screening coverage,and encourage age-appropriate women to receive the HPV vaccine.Future strategies should further explore approaches tailored to China's national conditions in order to reduce the incidence and mortality rates of cervical cancer,thereby improving women's quality of life.