四川天府新区直管区2014-2022年疑似预防接种异常反应监测分析

Analysis on the surveillance of adverse events following immunization in Sichuan Tianfu New District Directly Administered Area from 2014 to 2022

目的分析2014—2022年四川天府新区直管区疑似预防接种异常反应(AEFI)流行病学特征,为评价预防接种安全性提供依据。方法从中国疾病预防控制信息系统和四川省免疫规划信息管理系统收集AEFI数据以及接种数据,采用描述性流行病学方法分析。结果2014—2022年四川天府新区直管区共报告AEFI个案2003例,总报告发生率为75.06/10万,一般反应发生率68.65/10万,异常反应发生率5.17/10万。AEFI主要分布在2至4季度(85.72%)、华阳街道(55.16%)、3岁以下儿童(80.18%)。结论2014—2018年四川天府新区直管区AEFI监测敏感性较好,疫苗接种安全性良好,但仍需进一步加强培训,提升部分街道的监测敏感性,重点关注含麻疹成分疫苗的异常反应,提升预防接种工作人员AEFI应急处置能力。

Objective To analyze the characteristics of adverse events following immunization(AEFI)in Sichuan Tianfu New District Directly Administered Area from 2014 to 2022,so that to provide the basis for evaluating the safety of vaccination.Methods The data of AEFI cases reported and vaccination from 2014 to 2022 were collected from the Chinese National Notifiable Infectious Disease Reporting System and Sichuan Immunization Planning Information Management System for a descriptive epidemiological analysis.Results A total of 2003 AEFI cases were reported in Sichuan Tianfu New District Directly Administered Area from 2014 to 2022,with a total reported incidence of 75.06/105 doses.The incidence of general reactions was 68.65/105 doses,and the incidence of abnormal reactions was 5.17/105 doses.Cases were mainly concentrated in the second to fourth quarters(85.72%),Huayang street(55.16%),and children under 3 years old(80.18%).Conclusions The sensitivity of AEFI surveillance is good in Sichuan Tianfu New District Directly Administered Area from 2014 to 2022.Vaccine safety is good.However,it is still necessary to strengthen the further training,enhance the monitoring sensitivity of some streets,focus on abnormal reactions to vaccines containing measles components,and enhance the AEFI emergency response capabilities of vaccination staff.