2020年某铁路企业体检职工血压与血糖血脂的典型相关分析

Canonical correlation analysis of blood pressure,blood glucose,and lipids in railway workers undergoing physical examination in 2020

目的了解2020年某地铁路职工血压水平和血糖血脂现况,探讨二组变量之间的相关性。方法调查某铁路企业2020年1月—2020年12月参与体检的在职职工61503人,分析其收缩压、舒张压、脉压差、体质量指数(BMI)、空腹血糖(FBG)、血清甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平,并运用Spearman相关性分析和典型相关分析探讨血压水平和血糖血脂两组变量间的相关关系。结果共收集体检者61503例为研究对象,其中男49681例,女11822例。正常血压21450例(34.90%),正常血压高值26289例(42.70%),高血压13764例(22.40%),男性高血压患病率明显高于女性(χ^(2)=1416.52,P<0.001)。Spearman相关性分析显示,收缩压、舒张压和脉压差均与年龄、BMI、FBG、TG、TC、LDL-C、HDL-C存在相关性(P<0.01)。典型相关分析显示,男性组第一对典型变量的相关系数为0.428(P<0.05),女性组第一对典型变量的相关系数为0.435(P<0.05),无论性别、血压变量组主要由收缩压反映,血糖血脂变量组主要由年龄和BMI反映,且TG与典型变量的相关性较TC、LDLC、HDL-C强。结论血压与血糖血脂二组变量之间具有典型相关关系,二者相互影响且后者对前者的影响更大,故在高血压日常防控和健康管理中应立足整体,尤其要注重BMI和TG对血压的综合作用,据此为铁路职工提供全面、精准的高血压防控方案。

Objective To identify the levels of blood pressure,blood glucose,and lipids in a group of railway workers from certain area in 2020,and explore the correlation among blood pressure,blood glucose,and lipids.Methods A total of 61503 railway workers who participated in physical examination from January 2020 to December 2020 were investigated.The following parameters were analyzed:systolic and diastolic blood pressure,pulse pressure difference,body mass index(BMI),and the levels of fasting blood glucose(FBG),triglycerides(TG),total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),and high-density lipoprotein cholesterol(HDL-C).Spearman's correlation and canonical correlation analyses were used to test the associations among blood pressure,blood levels of glucose and lipids.Results A total of 61503 individuals were studied,including 49681 males and 11822 females.There were 21450 cases of normotension(34.90%),26289 cases of high normotension(42.70%),and 13764 cases of hypertension(22.40%).The prevalence of hypertension was significantly higher in men than in women,with a statistically significant difference(P<0.001).Spearman's correlation analysis showed that the systolic blood pressure,the diastolic blood pressure,and the difference in pulse pressure were all correlated with age,BMI,FBG,TG,TC,LDLC,and HDL-C blood levels(P<0.01).Canonical correlation analysis showed that the correlation coefficient of the first pair of canonical variables was 0.428(P<0.05)in the male group and 0.435(P<0.05)in the female group.Regardless of gender,the group of blood pressure variables was mainly associated with the systolic blood pressure,while the group of glucose and lipid variables was mainly associated with age and BMI.Furthermore,the correlation between TG levels and the canonical variables was stronger than that of TC,LDL-C,and HDL-C blood levels.Conclusion There was a canonical correlation between blood pressure and blood levels of glucose and lipids.The two groups of variables affected each other and the latter had a greater impact on the former.Therefore,the daily prevention and control of hypertension and health management should be based on the whole individual.It should specifically focus on the integrated effects of BMI and TG levels on blood pressure,in order to provide railway workers with a comprehensive and accurate program for the prevention and control of hypertension.