厚朴排气合剂灌肠联合肠梗阻导管在小儿非绞窄性肠梗阻中的应用

Application of Intestinal Obstruction Catheter Combined with Enema with Chinese Herbs in Children with Non Strangulated Intestinal Obstruction

目的:探讨肠梗阻导管联合厚朴排气合剂灌肠在小儿非绞窄性肠梗阻的应用。方法:100例非绞窄性肠梗阻患儿随机分为一般灌肠组和厚朴排气组各50例,一般灌肠组给予温盐水灌肠和肥皂水灌肠治疗;厚朴排气组给予肠梗阻导管联合厚朴排气合剂灌肠治疗。观察两组患儿治疗前后血清炎性因子变化情况、腹胀缓解时间、自主排气时间、恢复饮食时间、气-液平面消失时间及临床治疗有效率。结果:厚朴排气组腹胀缓解时间、自主排气时间、恢复饮食时间、气-液平面消失时间均短于一般灌肠组(P<0.05);厚朴排气组治疗后血清肠脂肪酸结合蛋白(intestinal fatty acid binding protein,IFABP)、D-二聚体(D-dimer,D-D)、血小板与淋巴细胞比值(plateletlymphocyte ratio,PLR)、降钙素原(procalcitonin,PCT)水平均低于一般灌肠组(P<0.05);厚朴排气组临床治愈率和有效率均高于一般灌肠组(P<0.05)。结论:肠梗阻导管联合厚朴排气合剂灌肠可以有效缩短小儿非绞窄性肠梗阻腹胀、排气和恢复饮食时间,减轻炎性反应,临床疗效确切。

Objective:To explore the application of intestinal obstruction catheter combined with enema with Chinese herbs in children with non strangulated intestinal obstruction.Methods:100 children with non strangulated intestinal obstruction admitted to our hospital from July 2020 to July 2022 were selected as the study subjects.Randomly divided into general enema group(n=50)and Magnolia officinalis exhaust group(n=50),The general enema group was treated with warm saline enema and soapy water enema;The Houpu exhaust group was treated with intestinal obstruction catheter and Houpu exhaust mixture enema.The changes of serum inflammatory factors before and after treatment were analyzed;The time of relieving abdominal distension,time of spontaneous exhaust,time of resuming diet and time of disappearance of gas liquid level were collected in the two groups;The clinical treatment efficiency of the two groups was analyzed.Results:The relieving time of abdominal distension,the time of spontaneous exhaust,the time of resuming diet and the time of disappearance of gas liquid level in the exhaust group of Magnolia officinalis were shorter than those in the general enema group(P<0.05).The levels of IFABP,D-D,PLR and PCT in the exhaust group were lower than those in the general enema group(P<0.05).The clinical cure rate of Magnolia officinalis exhaust group was higher than that of general enema group(P<0.05).Conclusion:Intestinal obstruction catheter combined with traditional Chinese medicine enema of Magnolia officinalis can effectively shorten the time of abdominal distension,exhaust and diet recovery in children with non strangulated intestinal obstruction,reduce inflammatory reaction,and have a definite clinical effect.