前列腺癌早期诊断中多参数磁共振成像检查的作用

The role of multiparametric MRI imaging examination in the early diagnosis of prostate cancer

目的分析多参数磁共振成像(MRI)对前列腺癌的早期诊断价值。方法以61例疑似前列腺癌患者为研究对象,检查时间为2020年3月至2023年8月,对所有患者进行超声和多参数MRI检查,同时将手术病理结果作为金标准,对比2种方法疾病诊断结果,并对超声和多参数MRI检查的灵敏度、特异度、准确性、阳性预测值和阴性预测值进行对比,分析多参数MRI与病理诊断结果的一致性。结果多参数MRI检出真阳35例,真阴23例,假阳例数为1例,假阴例数为2例;超声检查对应例数为27例、16例、8例和10例;较之于超声检查,多参数MRI灵敏度、特异度、准确性、阳性预测值和阴性预测值更高,差异具有统计学意义(P<0.05);多参数MRI诊断结果与手术病理结果高度一致(Kappa=0.898)。结论多参数MRI可准确诊断早期前列腺癌,与超声诊断比较优势明显,可应用。

Objective To analyze the early diagnostic value of multi parameter magnetic resonance imaging(MRI)for prostate cancer.Methods A total of 61 suspected prostate cancer patients were selected as the study subjects,with examination time from March 2020 to August 2023.Ultrasound and multiparametric MRI examinations were performed on all patients,and the surgical pathological results were used as the gold standard to compare the disease diagnosis results of the two methods.The diagnostic efficacy(sensitivity,specificity,accuracy,positive predictive value,and negative predictive value)of ultrasound and multiparametric MRI examinations were compared,and the consistency between multiparametric MRI and pathological diagnosis results was analyzed.Results Multi parameter MRI detected 35 cases of true positive and 23 cases of true negative,with 1 case of false positive and 2 cases of false negative.The corresponding cases on ultrasound examination were 27,16,8,and 10.Compared to ultrasound examination,multi parameter MRI has higher sensitivity,specificity,accuracy,positive predictive value,and negative predictive value,with significant intergroup differences(P<0.05);The diagnostic results of multi parameter MRI are highly consistent with the surgical pathological results(kappa=0.898).Conclusion Multi parameter MRI can accurately diagnose early prostate cancer,with significant advantages over ultrasound diagnosis,and can be applied.