上焦宣痹汤联合穴位贴敷治疗儿童上气道咳嗽综合征湿热证的临床观察

Clinical study on the treatment for upper airway cough syndrome of damp-heat type in children with Shangjiao Xuanbi decoction and acupoint application

目的观察上焦宣痹汤联合穴位贴敷治疗儿童上气道咳嗽综合征湿热证的临床疗效。方法选择2021年1月至2023年7月江西中医药大学第二附属医院收治的上气道咳嗽综合征湿热证患儿80例为观察对象,随机分为对照组和观察组各40例。对照组患儿采用抗感染、抗过敏等常规对症治疗,观察组患儿在对照组基础上给予上焦宣痹汤联合穴位贴敷治疗。经上述治疗3个疗程后,采用视觉模拟量表(VAS)评分、主要临床症状分级评分进行评价,比较两组的临床疗效、不良反应和复发例数。结果观察组临床总有效率为95.0%(38/40),明显高于对照组80.0%(32/40),差异有统计学意义(P<0.05)。观察组临床症状积分显著低于对照组,差异有统计学意义(P<0.05)。两组治疗后VAS评分均低于治疗前,且观察组下降较对照组更显著,差异有统计学意义(P<0.05)。治疗期间两组不良反应发生率比较差异无统计学意义(P>0.05)。随访3个月观察组复发率为7.89%(3/38),明显低于对照组28.13%(9/32),差异有统计学意义(P<0.05)。结论上焦宣痹汤联合穴位贴敷治疗儿童上气道咳嗽综合征湿热证有效且安全,可以降低复发率,值得临床医师推广并应用。

Objective To observe the clinical efficacy of Shangjiao Xuanbi decoction and acupoint application in the treatment of upper airway cough syndrome(UACS)of damp-heat type in children.Methods From January 2021 to July 2023,80 cases of UACS of damp-heat type diagnosed in the pediatric outpatient clinic of the Second Affiliated Hospital of Jiangxi University of TCM were selected and were randomly divided into a control group and an observation group,with 40 cases in each group.The control group was given symptomatic treatment such as anti-infection and anti-allergy treatment,while the observation group was given Shangjiao Xuanbi decoction and acupoint application on this basis.After 3 courses of treatment the VAS scores and the scores of main clinical symptom grading were used for evaluation,and the clinical efficacy,adverse reactions and recurrence rate were compared.Results The total effectiveness rate was 95.0%(38/40)in the observation group,significantly higher than that in the control group(80.0%,32/40),and the difference was statistically significant(P<0.05).The clinical symptom score was significantly lower in the observation group than in the control group(P<0.05).The VAS scores of the two groups were lower after treatment than before treatment,and the score in the observation group was even lower(P<0.05).There was no statistical difference in the incidence rate of adverse reactions between the two groups during the treatment(P>0.05).The recurrence rate of the observation group in the 3-month follow-up was 7.89%(3/38),obviously lower than that of the control group(28.13%,9/32),and the difference was of statistical significance(P<0.05).Conclusion The combination of Shangjiao Xuanbi decoction and acupoint application is effective and safe in the treatment of UACS of damp-heat type in children,which can reduce the recurrence rate,and deserves clinical promotion and application.