许兰毛癣菌致不典型黄癣5例回顾性分析

A retrospective analysis of five cases of atypical favus caused by Trichophyton schoenleinii

目的:探讨许兰毛癣菌所致不典型黄癣病例的临床特征及真菌学检查特点。方法:回顾性分析2007年-2023年于复旦大学附属华山医院门诊经真菌学检查确诊的5例不典型黄癣患者的临床及真菌学检查特征、治疗方法及预后。结果:5例患者均为女性,其中3例患者为成人,2例为儿童;临床症状均不典型;病程迁延,病程>10年者有4例;采用特比萘芬或伊曲康唑口服治疗后均治愈;4例患者遗留瘢痕性秃发。结论:黄癣仍有散在发生,其临床症状不典型,容易被误诊,患者未能得到及时的诊断和治疗。在临床实践中皮肤科医生应借助真菌学检查手段,早期识别黄癣,减少疾病传播及瘢痕性秃发等不可逆后果的出现。

Objective:To investigate the clinical features and mycological characteristics of atypical favus caused by Trichophyton schoenleini.Methods:The clinical characteristics,mycological information,treatment methods,and prognoses of the five cases diagnosed from 2007 to 2023 in Huashan Hospital were retrospectively analyzed.Results:The five patients,including three adults and two children,were all females.All clinical symptoms were atypical.Four cases had a disease duration of more than 10 years.They were cured with oral treatment with terbinafine or itraconazole.Scarring alopecia was left in four patients.Conclusion:Favus still occurred sporadically.The skin lesions tend to be atypical and easy to be misdiagnosed.Earlier mycological examination should be performed to prevent the spread of favus and the formation of scars and alopecia.