非神经系统恶性肿瘤相关性脑梗死的临床特点及其相关危险因素分析

Clinical Characteristics and Related Risk Factors of Non Neurological Malignant Tumor Associated Cerebral Infarction

目的探讨非神经系统恶性肿瘤相关性脑梗死的临床特点及其相关危险因素。方法选择48例非神经系统恶性肿瘤相关性脑梗死患者作为研究组,48例单纯性脑梗死患者设为对照组,经医院电子病历系统收集、整理患者资料,调查非神经系统恶性肿瘤相关性脑梗死的临床特点及其相关危险因素。结果对比两组各项临床表现情况,无统计学差异(P均>0.05);研究组多发病灶、前后循环、双侧受累比例高于对照组,有统计学差异(P均<0.05);两组入院当天美国国立卫生研究院卒中量表(NIHSS)评分及糖尿病、高血脂、吸烟史、饮酒史、高血压占比比较,无统计学差异(P均>0.05);研究组血小板计数、血红蛋白检测值低于对照组,纤维蛋白原、D-二聚体检测值高于对照组,有统计学差异(P均<0.05)。结论非神经系统恶性肿瘤相关性脑梗死多为多发性病灶且前后循环、双侧受累比例较高,血液高凝可能是其发生的危险因素。

Objective To explore the clinical characteristics and related risk factors of non neurological malignant tumor associated cerebral infarction.Methods 48 patients with non neurological malignancy related cerebral infarction were selected as the research group,while 48 patients with simple cerebral infarction were set as the control group.Patient data were collected and organized through the hospital's electronic medical record system to investigate the clinical characteristics and related risk factors of non neurological malignancy related cerebral infarction.Results There was no statistically significant difference in the occurrence of various clinical manifestations between the 2 groups(P values>0.05);The proportion of multiple lesions,anterior and posterior circulation,and bilateral involvement in the study group was higher than that in the control group,with statistical differences(P values<0.05);In the study group,there was no statistical difference in the scores of NIHSS and the proportion of diabetes,hyperlipidemia,smoking,drinking and hypertension on the day of admission(P>0.05);The platelet count and hemoglobin detection values in the study group were lower than those in the control group,while the fibrinogen and D-dimer detection values were higher than those in the control group,with statistical differences(P values<0.05).Conclusion Non neurological malignant tumor related cerebral infarction is mostly multiple lesions with a high proportion of anterior and posterior circulation and bilateral involvement.High blood coagulation may be a risk factor for its occurrence.