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炎症因子预测骨关节炎患者科学运动疗效的研究进展

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摘要 骨关节炎(OA)是最常见的关节疾病,也是最常见的致残原因之一,目前OA的治疗方法包括基础、药物和外科治疗,通常以保守治疗为基石,其中运动疗法更是受到了越来越多的研究和关注。本综述从OA的炎症反应机制出发,关注疾病变化与炎症因子的关系,同时,明确不同运动频率、强度、时间、方式、量、进阶对OA患者的影响,将运动与炎症相联系,探索运动时OA患者体内炎症因子的变化。从而,根据炎症因子预测病情进展、评估运动疗效,协助临床医生认识OA的科学规律运动,为OA高危人群及患者开具个性化运动处方。
出处 《中华风湿病学杂志》 CAS CSCD 2024年第7期512-516,共5页 Chinese Journal of Rheumatology
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  • 1Hamerman D. Aging and osteoarthritis: basic mechanisms [J]. Am Geriatr Soc, 1993, 41: 760-70.
  • 2Haynes MK, Hume JB. Phenotypic characterization of inflammatory cells from osteoarthritic synovium and synovial fluids [J]. Clin Immunol, 2002, 105(3): 315.
  • 3Ushio S, Nomba M, Okura T, et al. Cloning of the cDNA for human IFN-γ inducing factor expression in Escherichia coli and studies on biologic activities of the ptotein [J]. Immunology, 1996, 156(11): 4274-9.
  • 4Lu Y, Wang WJ, Leng JH, et al. Inhibitory effect of triptolide on interleukin 18 and its receptor in rheumatoid arthritis synovial fibroblasts[J]. Inflamm Res, 2008, 57(6): 260-5.
  • 5Joosten L, Radstake TR, Lubberts E, et al. Association of interleukin-18 expression with enhance levels of both interleukin-1 beta and tumor necrosis factor alfha in knee synovial tissue of patients with rheumatoid arthfitis[J]. Arthritis Rheum, 2003, 48(2): 339-47.
  • 6Gracie JA, Forsey RL, Chan WJ, et al. A proinflammatary role for IL-18 in rheumatoid arthritis [J]. Clin Invet, 1999, 104 (10): 1393-401.
  • 7Mccoy J, Wicks J, Audoty L. The role ofprostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis [J]. J Clin Invest, 2002, 110(5): 651-8.
  • 8Mcevoy AN, Bresnihan B, Fitzgerald O, et al. Cyclooxygenase 2-derived prostaglandin E2 production by corticotrophin-releasing hormone contributes to the activated CAMP response element binding protein content in meumatoid arthritis synovial tissue [J]. Arthritis Rheum, 2004, 50(4): 1132-45.
  • 9Henrotin YE, Zheng SX, Labasse AH, et al. Modulation of human chondrocyte metabolism by recombinant human interform [J]. Osteoarthritis Cartilage, 2000, 8(6): 474-82.
  • 10Futani H, Okayama A, Matsui K, et al. Relation between interleukin-18 and PGE2 in synovial fluid of osteoarthritis: a potential therapeutic target of cartilage degradation [J]. Immunotherapy, 2002, 25(Suppl 1): S61-4.

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