乳癖合剂治疗女童单纯性乳房早发育肝郁痰湿壅滞型35例临床观察

Clinical observation on treating 35 cases of girls with simple premature breast development of liver depression and phlegm dampness stagnation type by RupiHeji(乳癖合剂)

目的观察乳癖合剂治疗女童单纯性乳房早发育肝郁痰湿壅滞型的临床疗效。方法选取2021年1月至2022年12月于高邮市中医医院儿科治疗的单纯性乳房早发育肝郁痰湿壅滞型女童70例,按照随机数字表法分为治疗组和对照组,各35例。对照组予心理疏导和生活方式的干预,治疗组在对照组的基础上口服乳癖合剂,2组均连续治疗2个月后统计疗效。结果治疗组总有效率为94.29%(33/35),显著高于对照组的68.57%(24/35),2组比较,差异有统计学意义(P<0.05)。治疗前2组的Tanner分期评分比较,差异无统计学意义(P>0.05),具有可比性;治疗后2组Tanner分期评分均较同组治疗前显著降低,差异均有统计学意义(P<0.05),且治疗组降低更显著(P<0.05)。结论乳癖合剂治疗女童单纯性乳房早发育肝郁痰湿壅滞型疗效确切,可显著降低Tanner分期评分,值得临床推广应用。

Objective eTo observe the clinical efficacy of RupiHeji(乳癖合剂)in the treatment of simple pre-mature breast development in girls of liver depression and phlegm dampness stagnation type.Methods From Janu-ary 2021 to December 2022,70 girls with simple premature breast development of liver depression and phlegm dampness stagnation type treated in the Department of Pediatrics,Gaoyou Hospital of Traditional Chinese Medicine were selected and divided into a treatment group and a control group according to the random number table method,with 35 cases in each group.The control group was given psychological counseling and lifestyle intervention.The treatment group was given oral RupiHeji on the basis of psychological counseling and lifestyle intervention in the control group.Both groups were treated continuously for 2 months.Results The total effective rate of the treatment group was 94.29%(33/35),which was significantly higher than 68.57%(24/35)of the control group.The difer-ence between the two groups was statistically significant(P<0.05).There was no significant difference in Tanner staging scores between the two groups before treatment(P>0.05),which was comparable.After treatment,the Tanner staging scores in the two groups were significantly decreased when compared with those in the same group before treatment,differences being significant(P<0.05),and the decrease in the treatment group was more signifi-cant(P<0.05).Conclusion RupiHeji is effective in the treatment of simple premature breast development in girls of liver depression and phlegm dampness stagnation type,and can significantly reduce the Tanner staging score,which is worthy of clinical application.