肠道微生态在急性白血病感染性并发症中的研究进展

Progress of gut microbiota in infectious complications of acute leukemia

感染是导致急性白血病患者早期死亡的重要原因,探索如何减少急性白血病强化疗过程中的感染性并发症具有重要的理论和现实意义。研究表明,白血病患者在接受治疗过程中肠道菌群发生了重大变化,急性白血病患者的肠道菌群改变与化疗后感染性并发症的发生密切相关。文章就急性白血病患者的肠道菌群特征、肠道菌群与感染性并发症的关系、恢复肠道菌群多样性的方法等进行综述。

Infection is an important cause of early death in patients with acute leukemia,and exploring how to reduce infectious complications during intensive chemotherapy for acute leukemia is of great theoretical and practical significances.Studies have shown that the intestinal flora of leukemia patients undergoes significant changes in the process of receiving treatment,and the changes in the intestinal flora of acute leukemia patients are closely related to the occurrence of infectious complications after chemotherapy.This article reviews the characteristics of intestinal flora,the relationship between intestinal flora and infectious complications,and the methods to restore the diversity of intestinal flora in acute leukemia patients.