关注膀胱尿路上皮癌分级和分期的若干重点和难点问题

Several key and difficult issues related to the grading of urothelial carcinoma of urinary bladder

分级和分期分别是非浸润性和浸润性尿路上皮癌最重要的预后决定因素,同时也是病理医师在尿路上皮癌日常实践诊断过程遇到的最常见的难点问题之一。新近,国际泌尿病理协会组织召集了针对尿路上皮癌诊断、分级和分期等诸多问题的调查和问卷会议,最终形成了系列的共识性意见。本文对该系列共识意见进行简要的梳理,并结合国内尿路上皮癌的病理诊断现状,简要评注在病理医师的日常实践诊断过程中如何应用该系列的共识意见,深入认识相关诊断问题以及开展相关临床病理研究,从而进一步解决问题。

Grading and staging are the most important prognostic factors for both non-invasive and invasive urothelial carcinomas,and are also one of the most common difficulties encountered by pathologists in the daily diagnostic practice of urothelial carcinoma.Recently,the International Society of Urological Pathology organized a survey and questionnaire conference on various issues related to the diagnosis,grading,and staging of urothelial carcinoma,and ultimately formed a series of consensus opinions.This article briefly summarizes the consensus opinions of this series,and combines them with the current pathological diagnosis status of urothelial carcinoma in China.It briefly comments on how to apply this series of consensus opinions in the daily diagnostic practice of pathologists,deeply understand relevant diagnostic problems,and carry out relevant clinical pathological research to further solve problems.