区域医疗中心背景下MDT诊疗模式腹膜后软组织肉瘤诊治1例

MDT treatment model for diagnosis and treatment of retroperitoneal soft tissue sarcoma in the context of a regional medical center:report of 1 case

目的探讨区域医疗中心背景下多学科团队(MDT)诊疗模式在腹膜后软组织肉瘤(RPS)治疗中的临床价值。方法总结2020年10月于复旦大学附属中山医院厦门医院就诊的1例MDT模式下RPS患者的诊治经过,并复习相关文献。结果患者为59岁男性,诊断为腹膜后INI-1缺失的差分化的肉瘤伴全身多发转移。经复旦大学附属中山医院上海总部与厦门医院多轮MDT讨论后,给予全身抗肿瘤治疗联合局部治疗。经积极治疗后,患者获得较好疗效。随访期间肝、肺部病灶缓慢增大,遂调整治疗方案,生存已超3年。结论RPS诊疗复杂,区域医疗中心背景下MDT模式有助于为患者制订最优治疗方案,可能使患者生存获益最大。

Objective To explore the clinical value of multidisciplinary team(MDT)treatment model for retroperitoneal soft tissue sarcoma(RPS)in the context of a regional medical center.Methods The diagnosis and treatment of a patient with RPS in MDT model who were admitted to Xiamen Branch,Zhongshan Hospital,Fudan University in October 2020 were summarized,and the literature was reviewed.Results The patient was a 59-year-old male,he was diagnosed with retroperitoneal INI-1-deficient poorly differentiated sarcoma with multiple systemic metastases.After several rounds of MDT discussions in Shanghai headquarter and Xiamen Branch of Zhongshan Hospital,Fudan University,the patient received systemic antitumor therapy combined with local therapy.After active treatment,the patient obtained a good curative effect.During the follow-up period,the liver and lung lesions slowly enlarged,and the treatment plan was adjusted.The patient had survived for more than 3 years.Conclusions The diagnosis and treatment of RPS is complex,and the MDT model in the context of a regional medical center can help to formulate the optimal treatment plan for patients and may maximize the survival benefit of patients.